Disease: Amyotrophic Lateral Sclerosis
Source: ALL
Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Num. diseases
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06 614
rs6265
BDNF ; BDNF-AS
0.436 0.760 11 27658369 missense variant C/T snv 0.19 0.15 272
rs1800562
LOC108783645 ; HFE
0.435 0.880 6 26092913 missense variant G/A snv 3.3E-02 3.8E-02 262
rs759834365
BDNF-AS ; BDNF
0.448 0.760 11 27658456 missense variant C/T snv 1.2E-05 237
rs1799945
LOC108783645 ; HFE
0.452 0.760 6 26090951 missense variant C/G;T snv 0.11 0.10 226
rs121912438
SOD1
0.605 0.520 21 31667299 missense variant G/A;C;T snv 1.2E-05; 8.0E-06 58
rs75932628
LOC105375056 ; TREM2
0.662 0.480 6 41161514 missense variant C/A;T snv 6.8E-05; 2.6E-03 28
rs5848
FAM171A2 ; GRN
0.708 0.120 17 44352876 3 prime UTR variant C/T snv 0.41 17
rs121912443
SOD1
0.732 0.160 21 31663857 missense variant A/G snv 15
rs121909329
VCP
0.763 0.200 9 35065363 missense variant C/A;G;T snv 11
rs1424266770
CASP3
0.790 0.200 4 184632307 missense variant C/G snv 8.0E-06 10
rs121912442
SOD1 ; LOC102724449
0.807 0.120 21 31659783 missense variant C/T snv 3.6E-05 7
rs35801418
LRRK2
0.827 0.120 12 40321114 missense variant A/G snv 7
rs200161705
NEK1
0.882 0.160 4 169585374 missense variant C/A;T snv 6.0E-05; 2.3E-03 5
rs1272951905
MTHFSD
0.925 0.160 16 86532210 missense variant C/T snv 2.1E-05 3
rs2275294
ZNF512B
0.925 0.080 20 63962894 intron variant G/A snv 0.25 3
rs407135
SLC11A2
0.925 0.120 12 51017570 intron variant G/T snv 0.74 3
rs771845093
MFN2
0.925 0.160 1 12005903 missense variant G/A snv 8.0E-06 7.0E-06 3
rs1360444859
SPSB3 ; IGFALS
1.000 0.080 16 1791721 missense variant T/C snv 1.2E-05 2
rs149215094
VAPB
1.000 0.080 20 58444203 missense variant G/A snv 5.6E-05 5.6E-05 2