HFE, homeostatic iron regulator, 3077

N. diseases: 415; N. variants: 59
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C4529962
Disease: Fatty Liver Disease
Fatty Liver Disease
disease Disease or Syndrome 741 81 0.100 None 1.000 10 4 1999 2012
Malignant neoplasm of colon and/or rectum
disease Neoplastic Process 3669 502 0.080 None 1.000 8 2 2003 2015
CUI: C0428883
Disease: Diastolic blood pressure
Diastolic blood pressure
phenotype Clinical Attribute 507 1037 0.100 None 1.000 6 2 2011 2018
Finding of Mean Corpuscular Hemoglobin
phenotype Finding 653 1206 0.400 moderate 1.000 6 4 2010 2018
CUI: C0518015
Disease: Hemoglobin measurement
Hemoglobin measurement
phenotype Laboratory Procedure 131 224 0.100 None 1.000 5 3 2009 2017
CUI: C0871470
Disease: Systolic Pressure
Systolic Pressure
phenotype Clinical Attribute 843 1931 0.100 None 1.000 5 1 2011 2018
Low density lipoprotein cholesterol measurement
phenotype Laboratory Procedure 483 1142 0.100 None 1.000 4 2 2010 2019
CUI: C0524587
Disease: Mean Corpuscular Volume (result)
Mean Corpuscular Volume (result)
phenotype Laboratory or Test Result 269 549 0.100 None 1.000 4 1 2009 2012
Corpuscular Hemoglobin Concentration Mean
phenotype Laboratory or Test Result 401 4389 0.100 None 1.000 4 10 2010 2018
CUI: C0018935
Disease: Hematocrit procedure
Hematocrit procedure
phenotype Laboratory Procedure 138 216 0.100 None 1.000 3 2 2009 2017
CUI: C0373607
Disease: Ferritin measurement
Ferritin measurement
phenotype Laboratory Procedure 10 21 0.100 None 1.000 3 2 2011 2017
CUI: C0696113
Disease: Serum ferritin measurement
Serum ferritin measurement
phenotype Laboratory Procedure 10 21 0.100 None 1.000 3 2 2011 2017
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
phenotype Neoplastic Process 6626 169 0.030 None 1.000 3 2017 2019
CUI: C1318312
Disease: Serum iron measurement
Serum iron measurement
phenotype Laboratory Procedure 17 25 0.100 None 1.000 3 2 2011 2017
CUI: C1445957
Disease: Serum total cholesterol measurement
Serum total cholesterol measurement
phenotype Laboratory Procedure 486 1243 0.100 None 1.000 3 1 2010 2018
CUI: C2239101
Disease: Hemoglobin, CTCAE
Hemoglobin, CTCAE
phenotype Finding 7 26 0.100 None 1.000 3 2 2009 2012
CUI: C0005823
Disease: Blood Pressure
Blood Pressure
phenotype Organism Function 109 220 0.100 None 1.000 2 1 2011 2011
CUI: C0014772
Disease: Red Blood Cell Count measurement
Red Blood Cell Count measurement
phenotype Laboratory Procedure 717 1599 0.100 None 1.000 2 6 2009 2016
CUI: C0428474
Disease: Serum LDL cholesterol measurement
Serum LDL cholesterol measurement
phenotype Laboratory Procedure 269 555 0.100 None 1.000 2 1 2010 2013
Total iron binding capacity function
phenotype Clinical Attribute 20 35 0.100 None 1.000 2 1 2011 2017
CUI: C0751606
Disease: Adult Acute Lymphocytic Leukemia
Adult Acute Lymphocytic Leukemia
disease Neoplastic Process 860 154 0.020 None 1.000 2 6 2005 2006
CUI: C1277709
Disease: Transferrin saturation measurement
Transferrin saturation measurement
phenotype Laboratory Procedure 26 36 0.100 None 1.000 2 2 2014 2017
Iron binding capacity total measurement
phenotype Laboratory Procedure 20 35 0.100 None 1.000 2 1 2011 2017
CUI: C1611743
Disease: Familial (FPAH)
Familial (FPAH)
disease Disease or Syndrome 1075 276 0.020 None 1.000 2 2 1999 2000
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection
disease Disease or Syndrome 695 94 0.020 None 1.000 2 2005 2018