OPRK1, opioid receptor kappa 1, 4986

N. diseases: 156; N. variants: 12
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C1262019
Disease: Uremic pruritus
Uremic pruritus 		phenotype Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases Sign or Symptom 2 0.010 None 1.000 1 2018 2018
CUI: C4237239
Disease: Opioid use disorder, severe
Opioid use disorder, severe 		disease Mental or Behavioral Dysfunction 2 0.010 None 1.000 1 2019 2019
CUI: C0027609
Disease: Neonatal Abstinence Syndrome
Neonatal Abstinence Syndrome 		disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Chemically-Induced Disorders; Mental Disorders Disease or Syndrome 9 3 0.020 None 1.000 2 1 2015 2018
CUI: C0221776
Disease: Oral pain
Oral pain 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 11 0.010 None 1.000 1 2019 2019
CUI: C0029104
Disease: Opioid withdrawal
Opioid withdrawal 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 16 0.010 None 1.000 1 2014 2014
CUI: C2004461
Disease: Bowel dysfunction
Bowel dysfunction 		disease Digestive System Diseases Disease or Syndrome 16 1 0.010 None 1.000 1 2018 2018
CUI: C0871099
Disease: positive and negative symptoms
positive and negative symptoms 		phenotype Sign or Symptom 18 5 0.010 None 1.000 1 2019 2019
CUI: C1301797
Disease: Induced hypothermia (finding)
Induced hypothermia (finding) 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 21 0.010 None 1.000 1 2019 2019
CUI: C0233477
Disease: Dysphoric mood
Dysphoric mood 		disease Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 22 6 0.100 None 1.000 10 2017 2019
CUI: C0028047
Disease: Nicotine withdrawal
Nicotine withdrawal 		disease Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 27 1 0.010 None 1.000 1 2019 2019
CUI: C0240602
Disease: opioid use
opioid use 		disease Mental or Behavioral Dysfunction 39 5 0.010 None 1.000 1 2017 2017
CUI: C0008060
Disease: child abuse behavior
child abuse behavior 		phenotype Mental or Behavioral Dysfunction 40 11 0.010 None 1.000 1 2018 2018
CUI: C0391976
Disease: Pain Disorder
Pain Disorder 		disease Mental Disorders Mental or Behavioral Dysfunction 41 3 0.020 None 1.000 2 2018 2018
CUI: C0376338
Disease: Diagnosis, Psychiatric
Diagnosis, Psychiatric 		disease Mental Disorders Mental or Behavioral Dysfunction 46 1 0.010 None 1.000 1 2001 2001
CUI: C0234238
Disease: Ache
Ache 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 50 0.300 None 1.000 1 1998 1998
CUI: C0458257
Disease: Pain, Splitting
Pain, Splitting 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 50 0.300 None 1.000 1 1998 1998
CUI: C0458259
Disease: Pain, Crushing
Pain, Crushing 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 50 0.300 None 1.000 1 1998 1998
CUI: C0751407
Disease: Pain, Migratory
Pain, Migratory 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 50 0.300 None 1.000 1 1998 1998
CUI: C0751408
Disease: Suffering, Physical
Suffering, Physical 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 50 0.300 None 1.000 1 1998 1998
CUI: C0234254
Disease: Radiating pain
Radiating pain 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 51 0.300 None 1.000 1 1998 1998
CUI: C0184567
Disease: Acute onset pain
Acute onset pain 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 53 6 0.010 None 1.000 1 2019 2019
CUI: C0234230
Disease: Pain, Burning
Pain, Burning 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 56 0.300 None 1.000 1 1998 1998
CUI: C0424166
Disease: Social Anxiety
Social Anxiety 		disease Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 57 6 0.010 None 1.000 1 2020 2020
CUI: C0086189
Disease: Drug Withdrawal Symptoms
Drug Withdrawal Symptoms 		phenotype Chemically-Induced Disorders; Mental Disorders Sign or Symptom 58 0.300 None 1.000 2 1998 2010
CUI: C0234245
Disease: Visceral Pain
Visceral Pain 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 58 0.020 None 1.000 2 1998 2008