OPRK1, opioid receptor kappa 1, 4986

N. diseases: 156; N. variants: 12
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C0234238
Disease: Ache
Ache 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 50 0.300 None 1.000 1 1998 1998
CUI: C0234254
Disease: Radiating pain
Radiating pain 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 51 0.300 None 1.000 1 1998 1998
CUI: C0234230
Disease: Pain, Burning
Pain, Burning 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 56 0.300 None 1.000 1 1998 1998
CUI: C0458259
Disease: Pain, Crushing
Pain, Crushing 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 50 0.300 None 1.000 1 1998 1998
CUI: C0751407
Disease: Pain, Migratory
Pain, Migratory 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 50 0.300 None 1.000 1 1998 1998
CUI: C0751408
Disease: Suffering, Physical
Suffering, Physical 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 50 0.300 None 1.000 1 1998 1998
CUI: C0458257
Disease: Pain, Splitting
Pain, Splitting 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 50 0.300 None 1.000 1 1998 1998
CUI: C0020505
Disease: Hyperphagia
Hyperphagia 		phenotype Pathological Conditions, Signs and Symptoms Finding 60 3 0.200 None 1.000 1 1998 1998
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases Sign or Symptom 451 4 0.200 None 1.000 1 2006 2006
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		disease Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases Disease or Syndrome 1800 680 0.200 None 1.000 1 2004 2004
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		disease Nutritional and Metabolic Diseases; Endocrine System Diseases Experimental Model of Disease 522 0.200 None 1.000 1 2006 2006
CUI: C0242596
Disease: Neoplasm, Residual
Neoplasm, Residual 		phenotype Pathological Conditions, Signs and Symptoms; Neoplasms Neoplastic Process 329 23 0.010 None 1.000 1 1995 1995
CUI: C0279530
Disease: Malignant Bone Neoplasm
Malignant Bone Neoplasm 		disease Neoplasms; Musculoskeletal Diseases Neoplastic Process 125 0.010 None 1.000 1 2018 2018
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		disease Mental Disorders Mental or Behavioral Dysfunction 1630 348 0.010 None 1.000 1 2018 2018
CUI: C0038436
Disease: Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder 		disease Mental Disorders Mental or Behavioral Dysfunction 418 117 0.010 None 1.000 1 2019 2019
CUI: C0376338
Disease: Diagnosis, Psychiatric
Diagnosis, Psychiatric 		disease Mental Disorders Mental or Behavioral Dysfunction 46 1 0.010 None 1.000 1 2001 2001
CUI: C0424166
Disease: Social Anxiety
Social Anxiety 		disease Behavior and Behavior Mechanisms Mental or Behavioral Dysfunction 57 6 0.010 None 1.000 1 2020 2020
CUI: C0424295
Disease: Hyperactive behavior
Hyperactive behavior 		phenotype Pathological Conditions, Signs and Symptoms; Nervous System Diseases Mental or Behavioral Dysfunction 1263 112 0.010 None 1.000 1 2013 2013
CUI: C0442874
Disease: Neuropathy
Neuropathy 		group Nervous System Diseases Disease or Syndrome 484 110 0.010 None 1.000 1 2019 2019
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		disease Nervous System Diseases; Cardiovascular Diseases Disease or Syndrome 1159 704 0.010 None 1.000 1 2019 2019
CUI: C4237239
Disease: Opioid use disorder, severe
Opioid use disorder, severe 		disease Mental or Behavioral Dysfunction 2 0.010 None 1.000 1 2019 2019
CUI: C0242510
Disease: Drug usage
Drug usage 		phenotype Chemically-Induced Disorders; Mental Disorders Mental or Behavioral Dysfunction 170 21 0.010 None 1.000 1 2018 2018
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression 		disease Mental Disorders Mental or Behavioral Dysfunction 641 225 0.010 None 1.000 1 2018 2018
CUI: C0149931
Disease: Migraine Disorders
Migraine Disorders 		group Nervous System Diseases Disease or Syndrome 512 264 0.010 None 1.000 1 2017 2017
CUI: C0184567
Disease: Acute onset pain
Acute onset pain 		phenotype Pathological Conditions, Signs and Symptoms Sign or Symptom 53 6 0.010 None 1.000 1 2019 2019