SNCA, synuclein alpha, 6622

N. diseases: 449; N. variants: 66
Source: ALL
Disease Type Disease Class Semantic Type N. genes d N. SNPs d Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
CUI: C1611743
Disease: Familial (FPAH)
Familial (FPAH)
disease Disease or Syndrome 1075 276 0.100 None 0.986 71 4 1998 2020
CUI: C3160718
Disease: PARKINSON DISEASE, LATE-ONSET
PARKINSON DISEASE, LATE-ONSET
disease Disease or Syndrome 247 76 0.100 None 0.971 35 2 2003 2020
CUI: C0426980
Disease: Motor symptoms
Motor symptoms
phenotype Sign or Symptom 100 15 0.100 None 0.955 22 2 2010 2020
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder)
disease Disease or Syndrome 1 5 0.900 None 1.000 9 5 1997 2015
CUI: C0236734
Disease: Caffeine related disorders
Caffeine related disorders
group Mental or Behavioral Dysfunction 360 56 0.040 None 0.500 4 1 2015 2019
CUI: C0349081
Disease: Dementia in Parkinson's disease
Dementia in Parkinson's disease
disease Disease or Syndrome 9 2 0.040 None 1.000 4 2007 2012
CUI: C4020732
Disease: Mitochondrial abnormalities
Mitochondrial abnormalities
disease Anatomical Abnormality 83 20 0.040 None 1.000 4 2 2007 2016
Behavioral and psychological symptoms of dementia
phenotype Sign or Symptom 72 9 0.030 None 1.000 3 2015 2020
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement
phenotype Laboratory Procedure 1156 2575 0.100 None 1.000 2 3 2018 2018
CUI: C3825201
Disease: Mitochondrial pathology
Mitochondrial pathology
phenotype Disease or Syndrome 20 6 0.020 None 1.000 2 2004 2018
Malignant neoplasm of colon and/or rectum
disease Neoplastic Process 3669 502 0.020 None 1.000 2 2015 2018
CUI: C0221505
Disease: Lesion of brain
Lesion of brain
group Disease or Syndrome 188 9 0.010 None 1.000 1 2001 2001
CUI: C0278678
Disease: Metastatic Renal Cell Cancer
Metastatic Renal Cell Cancer
disease Neoplastic Process 145 9 0.010 None 1.000 1 2019 2019
CUI: C0334070
Disease: Maturation defect
Maturation defect
phenotype Acquired Abnormality 43 2 0.010 None 1.000 1 2018 2018
CUI: C0338460
Disease: Argyrophilic grain disease
Argyrophilic grain disease
disease Disease or Syndrome 18 7 0.010 None 1.000 1 2017 2017
Nicotinamide adenine dinucleotide coenzyme Q reductase deficiency
disease Disease or Syndrome 51 4 0.010 None 1.000 1 2015 2015
CUI: C0564567
Disease: Impulsive character (finding)
Impulsive character (finding)
phenotype Mental or Behavioral Dysfunction 52 19 0.010 None 1.000 1 2019 2019
CUI: C0748903
Disease: spinal cord involvement
spinal cord involvement
disease Disease or Syndrome 9 0.010 None 1.000 1 2019 2019
CUI: C0860603
Disease: Anxiety symptoms
Anxiety symptoms
phenotype Sign or Symptom 110 10 0.010 None 1.000 1 1 2018 2018
CUI: C0877008
Disease: Enzyme inhibition disorder
Enzyme inhibition disorder
phenotype Disease or Syndrome 171 1 0.010 None 1.000 1 2015 2015
[D]Sleep disturbances (& [hypersomnia] or [insomnia])
phenotype Sign or Symptom 69 23 0.010 None 1.000 1 1 2013 2013
CUI: C1112261
Disease: Gaze palsy
Gaze palsy
disease Disease or Syndrome 3 0.010 None 1.000 1 1998 1998
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
phenotype Neoplastic Process 6626 169 0.010 None 1.000 1 2018 2018
CUI: C1535950
Disease: Gastrointestinal inflammation
Gastrointestinal inflammation
disease Disease or Syndrome 39 0.010 None 1.000 1 2019 2019
CUI: C1695782
Disease: Cerebral hypoperfusion
Cerebral hypoperfusion
disease Disease or Syndrome 40 1 0.010 None 1.000 1 2019 2019