Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.080 AlteredExpression disease BEFREE Event-free survival of infants and toddlers enrolled in the HR-NBL-1/SIOPEN trial is associated with the level of neuroblastoma mRNAs at diagnosis. 29603574 2018
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.080 Biomarker disease BEFREE Thirteen other TGFβ regulators (Chordin, Chordin-like 1, Chordin-like 2, Differential screening-selected gene aberrative in neuroblastoma [DAN], Decorin, Endoglin, Follistatin-like 1, Follistatin-like 3, Follistatin-like 4, Noggin, α2 macroglobulin, TGFβ receptor 3, Von Willebrand factor C domain-containing 2) had little or no effect. 28500669 2017
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.080 GeneticVariation disease BEFREE Bone morphogenetic proteins (BMPs) are regulated by extracellular antagonists of the DAN (differential screening-selected gene aberrative in neuroblastoma) family. 28104757 2017
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.080 AlteredExpression disease BEFREE Using a biotinylated NBL-1 complexed with plasmid DNAs based on electrostatic interaction through avidin-conjugated polylysines, exogenous luciferase genes were expressed in neuroblastoma cells at a more than 10-fold higher level. 10811228 2000
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.080 Biomarker disease BEFREE Down-regulation of protein kinase C alpha and gamma and enhanced TPA-induced neurite formation in DAN-transfected neuroblastoma cells. 9862417 1998
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.080 Biomarker disease BEFREE The forced expression of DAN gene enhanced the neurite extension in the presence of RA, suggesting that DAN gene product might contain some regulatory role(s) in the RA-induced cellular differentiation in neuroblastoma cells. 9500977 1998
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.080 GeneticVariation disease BEFREE Genomic Southern experiments demonstrated that the allelic loss of DAN gene might occur in neuroblastoma. 9324305 1997
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.080 Biomarker disease BEFREE Collectively, we propose that human DAN gene is a possible candidate for a tumor suppressor gene of human neuroblastoma. 8084583 1994