CDKN1A, cyclin dependent kinase inhibitor 1A, 1026

N. diseases: 490; N. variants: 17
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.340 Biomarker group BEFREE Immunohistochemistry (IHC) revealed decreased levels of Cul4A-associated proteins p21(CIP1) and tumour suppressor p19(ARF) in the lung tumours, suggesting that Cul4A regulated their expression in these tumours. 24648314 2014
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.340 Biomarker group CTD_human Haem oxygenase-1 plays a central role in NNK-mediated lung carcinogenesis. 18508827 2008
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.340 GeneticVariation group LHGDN Comprehensive assessment of P21 polymorphisms and lung cancer risk. 18046503 2008
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.340 AlteredExpression group LHGDN Elevated p53 and p21waf1 mRNA expression in blood lymphocytes from lung cancer patients with chemoresistance. 18035504 2007
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.340 Biomarker group CTD_human Lung tumors were the predominant tumor type in urethane-treated mice regardless of p21(Cip1) status. 12466968 2002
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.340 Biomarker group LHGDN H(2)O(2)-induced AP-1 activation and its effect on p21(WAF1/CIP1)-mediated G2/M arrest in a p53-deficient human lung cancer cell. 12054510 2002