|
Mammary Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
In both cell lines and primary patient samples, we observed consistent expression patterns of these biomarkers varies by cancer indication, such that ERBB3 and CDKN1B expression are relatively high in breast tumors while EGFR expression is relatively high in other indications.
|
27035903 |
2016 |
|
Mammary Neoplasms
|
0.400 |
AlteredExpression
|
group |
BEFREE |
The correlation between p27KIP1 expression and rapamycin antitumor activity was also observed in the patient-derived breast tumor xenograft models.
|
25744729 |
2015 |
|
Mammary Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1).
|
24457952 |
2014 |
|
Mammary Neoplasms
|
0.400 |
AlteredExpression
|
group |
BEFREE |
High Cks1 expression is associated with aggressive breast tumors and correlates with low p27Kip1 levels in some cases, although it is also an independent prognostic marker for survival, and provides predictive information in addition to that provided by p27Kip1 alone.
|
19360356 |
2009 |
|
Mammary Neoplasms
|
0.400 |
Biomarker
|
group |
LHGDN |
MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1.
|
18708351 |
2008 |
|
Mammary Neoplasms
|
0.400 |
Biomarker
|
group |
LHGDN |
Polymorphisms cMyc-N11S and p27-V109G and breast cancer risk and prognosis.
|
17567920 |
2007 |
|
Mammary Neoplasms
|
0.400 |
AlteredExpression
|
group |
LHGDN |
PKCtheta promotes c-Rel-driven mammary tumorigenesis in mice and humans by repressing estrogen receptor alpha synthesis.
|
18037997 |
2007 |
|
Mammary Neoplasms
|
0.400 |
Biomarker
|
group |
LHGDN |
Genetic screening reveals an essential role of p27kip1 in restriction of breast cancer progression.
|
17804714 |
2007 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Variant genotypes of CDKN1A and CDKN1B are associated with an increased risk of breast cancer in Chinese women.
|
16804901 |
2006 |
|
Mammary Neoplasms
|
0.400 |
AlteredExpression
|
group |
LHGDN |
p27(Kip1) and cyclin E expression and breast cancer survival after treatment with adjuvant chemotherapy.
|
17148774 |
2006 |
|
Mammary Neoplasms
|
0.400 |
Biomarker
|
group |
CTD_human |
Downregulation of the cyclin-dependent kinase inhibitor p27kip1 might correlate with poor disease-free and overall survival in inflammatory breast cancer.
|
17092400 |
2006 |
|
Mammary Neoplasms
|
0.400 |
AlteredExpression
|
group |
LHGDN |
Prognostic impact of Skp2 and p27 in human breast cancer.
|
16636894 |
2006 |
|
Mammary Neoplasms
|
0.400 |
Biomarker
|
group |
LHGDN |
TNFalpha resistance in MCF-7 breast cancer cells is associated with altered subcellular localization of p21CIP1 and p27KIP1.
|
15592362 |
2005 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Molecular analysis of the p27/kip1 gene in breast cancer.
|
16035731 |
2005 |
|
Mammary Neoplasms
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Inducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells.
|
15996662 |
2005 |
|
Mammary Neoplasms
|
0.400 |
AlteredExpression
|
group |
LHGDN |
Jun activation domain binding protein 1 expression is associated with low p27(Kip1)levels in node-negative breast cancer.
|
14654548 |
2003 |
|
Mammary Neoplasms
|
0.400 |
AlteredExpression
|
group |
LHGDN |
Estrogens down-regulate p27Kip1 in breast cancer cells through Skp2 and through nuclear export mediated by the ERK pathway.
|
12904306 |
2003 |
|
Mammary Neoplasms
|
0.400 |
PosttranslationalModification
|
group |
LHGDN |
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer.
|
12244303 |
2002 |
|
Mammary Neoplasms
|
0.400 |
AlteredExpression
|
group |
LHGDN |
PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest.
|
12244302 |
2002 |