CDKN2A, cyclin dependent kinase inhibitor 2A, 1029

N. diseases: 1314; N. variants: 146
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.450 PosttranslationalModification group BEFREE We successfully analyzed the methylation patterns of P16 gene for three cases of stomach tumor tissues. 18228535 2008
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.450 Biomarker group CTD_human Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray. 16367923 2006
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.450 PosttranslationalModification group LHGDN Detection of p16 promoter hypermethylation in serum of gastric cancer patients. 12824886 2003
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.450 GeneticVariation group LHGDN Studies on microsatellite instability in p16 gene and expression of hMSH2 mRNA in human gastric cancer tissues. 12632492 2003
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.450 AlteredExpression group BEFREE Quantitative reverse transcription PCR (RT-PCR) was used to measure gene expressions (relative mRNA levels) of p16 and the alternate transcript pl6beta in esophageal and gastric tumors. p16 gene expression was undetectable in 13 of 25 esophageal squamous cell carcinomas. 9333024 1997
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.450 GeneticVariation group BEFREE Thirty-six primary gastric tumors and 9 gastric carcinoma cell lines were examined for alterations of the p16 and p15 genes. 9366289 1997
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.450 Biomarker group HPO