Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004096
Disease: Asthma
Asthma
0.100 GeneticVariation disease GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738 2019
CUI: C0004096
Disease: Asthma
Asthma
0.100 GeneticVariation disease GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474 2019
CUI: C0014772
Disease: Red Blood Cell Count measurement
Red Blood Cell Count measurement
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0035242
Disease: Respiratory Tract Diseases
Respiratory Tract Diseases
0.100 GeneticVariation group GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0264408
Disease: Childhood asthma
Childhood asthma
0.100 GeneticVariation disease GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738 2019
CUI: C0871470
Disease: Systolic Pressure
Systolic Pressure
0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0018681
Disease: Headache
Headache
0.100 GeneticVariation phenotype GWASCAT A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N=223,773). 29397368 2018
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement
0.100 GeneticVariation phenotype GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576 2018
CUI: C0149931
Disease: Migraine Disorders
Migraine Disorders
0.100 GeneticVariation group GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2016
CUI: C0149931
Disease: Migraine Disorders
Migraine Disorders
0.100 GeneticVariation group GWASCAT Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine. 27322543 2016
Platelet mean volume determination (procedure)
0.100 GeneticVariation phenotype GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
CUI: C0149931
Disease: Migraine Disorders
Migraine Disorders
0.100 GeneticVariation group GWASCAT Genome-wide meta-analysis identifies new susceptibility loci for migraine. 23793025 2013
CUI: C0149931
Disease: Migraine Disorders
Migraine Disorders
0.100 GeneticVariation group GWASDB Genome-wide meta-analysis identifies new susceptibility loci for migraine. 23793025 2013
CUI: C0032176
Disease: Platelet aggregation
Platelet aggregation
0.100 GeneticVariation phenotype GWASDB Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists. 20526338 2010
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.010 AlteredExpression phenotype BEFREE miR-940 potentially promotes proliferation and metastasis of endometrial carcinoma through regulation of MRVI1. 31085718 2019
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.010 AlteredExpression disease BEFREE First, we assessed the expression of miR-940 and MRVI1 in EC tissues collected from The Cancer Genome Atlas (TCGA) database and EC cell lines. miR-940 was significantly overexpressed in EC tissues and cell lines, particularly in RL95-2 cells. 31085718 2019
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.010 AlteredExpression phenotype BEFREE Moreover, forced expression of MRVI1 in miR-940 mimic transfected cells abolished the facilitation of miR-940 on cell proliferation, migration, and invasion of RL95-2 and KLE cells. 31085718 2019
CUI: C0026654
Disease: Moyamoya Disease
Moyamoya Disease
0.010 GeneticVariation disease BEFREE The rs35857561 polymorphism in MRVI1 may be a genetic susceptibility factor for moyamoya in European patients with neurofibromatosis type 1. 30001348 2018
CUI: C0027831
Disease: Neurofibromatosis 1
Neurofibromatosis 1
0.010 GeneticVariation disease BEFREE The rs35857561 polymorphism in MRVI1 may be a genetic susceptibility factor for moyamoya in European patients with neurofibromatosis type 1. 30001348 2018
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.010 Biomarker disease BEFREE More recently, further genes in the pathway encoding the endothelial nitric oxide synthase, the phosphodiesterases 3A and 5A, and the inositol 1,4,5-trisphosphate receptor I-associated protein (IRAG), i.e., NOS3, PDE3A, PDE5A, and MRVI1, respectively, were likewise identified as CAD risk genes. 29601927 2018
CUI: C0040053
Disease: Thrombosis
Thrombosis
0.010 Biomarker phenotype LHGDN These findings reveal that interaction between IRAG and InsP3RI has a central role in NO/cGMP-dependent inhibition of platelet aggregation and in vivo thrombosis. 16990611 2007
CUI: C0023418
Disease: leukemia
leukemia
0.010 Biomarker disease BEFREE One new site, Mrvi1 was identified that was disrupted by MRV in two of the leukemias. 10321731 1999
CUI: C0023470
Disease: Myeloid Leukemia
Myeloid Leukemia
0.010 AlteredExpression disease BEFREE Taken together, these data suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation. 10321731 1999
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.010 Biomarker group BEFREE Experiments are in progress to test whether Mrvi1 is a tumor suppressor gene. 10321731 1999