|
Bacteremia
|
0.040 |
Biomarker
|
disease |
BEFREE |
The genomic analysis of three isolates (from blood culture, nasal and anal swabs) showed that the bacteremia was caused by a KPC-2 producing extensively drug-resistant K64-ST11 hypermucousviscous <i>K. pneumoniae</i> (hmKP) harboring several virulence and antimicrobial resistance genes.
|
30298131 |
2018 |
|
Bacteremia
|
0.040 |
Biomarker
|
disease |
BEFREE |
Central venous catheter, mechanical ventilation, high Pitt bacteraemia score, hospitalization prior to culture, and prior antibiotic use (carbapenem, aminoglycoside and tigecycline) were identified as independent risk factors for carbapenem-non-susceptible K. pneumoniae BSI, which was mostly caused by KPC-2 in northern China.
|
29303020 |
2018 |
|
Bacteremia
|
0.040 |
Biomarker
|
disease |
BEFREE |
This is the first report of KPC-2 K. pneumoniae from bacteremia in India.
|
29787365 |
2018 |
|
Bacteremia
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
Treatment failures of a carbapenem-colistin regimen among patients with bacteremia due to sequence type 258 (ST258), KPC-2-producing Klebsiella pneumoniae were significantly more likely if both agents were inactive in vitro, as defined by a colistin MIC of >2 μg/ml and the presence of either a major ompK36 porin mutation (guanine and alanine insertions at amino acids 134 and 135 [ins aa 134-135 GD], IS5 promoter insertion [P = 0.007]) or a doripenem MIC of >8 μg/ml (P = 0.01).
|
25534733 |
2015 |
|
Pneumonia
|
0.020 |
Biomarker
|
disease |
BEFREE |
ESBL-producing E. coli ST131 and multi-drug resistance ESBL-producing, as well as New Delhi metallo-β-lactamase-1 (NDM-1) and Klebsiella pneumoniae carbapenemases-2 (KPC-2) bearing K. pneumoniae ST11 are spreading in patients with pneumonia in hospital.
|
31408445 |
2019 |
|
Pneumonia
|
0.020 |
Biomarker
|
disease |
BEFREE |
KPC-2-producing Klebsiella pneumoniae infections in Greek hospitals are mainly due to a hyperepidemic clone.
|
19480809 |
2009 |
|
Meningitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
High prevalence of KPC-2-producing hypervirulent <i>Klebsiella pneumoniae</i> causing meningitis in Eastern China.
|
30936727 |
2019 |
|
Pneumonia, Ventilator-Associated
|
0.010 |
Biomarker
|
disease |
BEFREE |
This study evaluated the mechanism of ceftazidime/avibactam resistance in a KPC-2-expressing Klebsiella pneumoniae isolated from a patient following ceftazidime/avibactam combination therapy with gentamicin for the treatment of ventilator-associated pneumonia.
|
30753572 |
2019 |
|
Diarrhea
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
To our knowledge, this is only the second report of C. koseri producing KPC-2, and we report the first draft genome sequence of a bla<sub>KPC-2</sub>-carrying C. koseri isolate from a patient with diarrhoea in China.
|
30291901 |
2018 |
|
Parkinson Disease
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
This study reports the draft genome sequence of a KPC-2-producing K. pneumoniae strain (Kp10) simultaneously harbouring bla<sub>CTX-M-15</sub> and bla<sub>CTX-M-59</sub> genes isolated from urine culture of a patient with Parkinson's disease.
|
29476983 |
2018 |
|
Abdominal Abscess
|
0.010 |
Biomarker
|
disease |
BEFREE |
WGS showed that TVGHCRE225 acquired a novel hybrid virulence plasmid harbouring a set of virulence genes (iroBCDN, iucABCD, rmpA and rmpA2, and iutA) compared with the classic ST11 KPC-2-producing strain.
|
29800340 |
2018 |
|
Pneumonia due to Klebsiella pneumoniae
|
0.010 |
Biomarker
|
disease |
BEFREE |
Emergence of Carbapenemase Producing Klebsiella Pneumonia and Spread of KPC-2 and KPC-17 in Taiwan: A Nationwide Study from 2011 to 2013.
|
26384242 |
2015 |
|
Empyema
|
0.010 |
Biomarker
|
disease |
BEFREE |
Treatment of KPC-2 Enterobacter cloacae empyema with cefepime and levofloxacin.
|
24268534 |
2014 |
|
Lower urinary tract infectious disease
|
0.010 |
GeneticVariation
|
group |
BEFREE |
We report a case of lower urinary tract infection due to KPC-2-producing K. pneumoniae (KpCG02) in an elderly patient who had recently been hospitalized in Greece.
|
23313083 |
2013 |
|
Septicemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 beta-lactamase, was isolated from a patient with sepsis at a Boston hospital.
|
15504876 |
2004 |
|
Sepsis
|
0.010 |
Biomarker
|
disease |
BEFREE |
A strain of an Enterobacter sp. with reduced susceptibility to imipenem, which produced a plasmid-mediated class A carbapenem-hydrolyzing enzyme, KPC-2 beta-lactamase, was isolated from a patient with sepsis at a Boston hospital.
|
15504876 |
2004 |