UPK3B, uroplakin 3B, 105375355

N. diseases: 82; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.020 Biomarker group BEFREE CDK5 activation promotes ischemic neuronal death in stroke, with the recognized activation mechanism being calpain-dependent p35 cleavage to p25. 30158515 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.020 Biomarker group BEFREE The majority of patients demonstrated increased expression of Cdk5 and p-Cdk5 in stroke-affected tissue, with about a third showing increased p35 and p25 cleaved fragment as determined by Western blotting. 17493033 2007