Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0155912
Disease: Pulmonary Alveolar Microlithiasis
Pulmonary Alveolar Microlithiasis 		0.780 GeneticVariation disease BEFREE Pulmonary alveolar microlithiasis (PAM) is caused by genetic variants in the <i>SLC34A2</i> gene, which encodes the sodium-dependent phosphate transport protein 2B. 31831582 2020
CUI: C0155912
Disease: Pulmonary Alveolar Microlithiasis
Pulmonary Alveolar Microlithiasis 		0.780 GeneticVariation disease BEFREE Biallelic inactivating SLC34A2 mutations are found in patients with pulmonary alveolar microlithiasis, a lung disease characterized by the deposition of microcrystals. 30542787 2019
CUI: C0155912
Disease: Pulmonary Alveolar Microlithiasis
Pulmonary Alveolar Microlithiasis 		0.780 GeneticVariation disease BEFREE A mutation in the IIb sodium phosphate transporter SLC34A2 gene has recently been described in pulmonary alveolar microlithiasis (PAM) patients. 29375690 2018
CUI: C0155912
Disease: Pulmonary Alveolar Microlithiasis
Pulmonary Alveolar Microlithiasis 		0.780 GermlineCausalMutation disease ORPHANET SLC34A2 Gene mutation of pulmonary alveolar microlithiasis: report of four cases and review of literatures. 23164546 2013
CUI: C0155912
Disease: Pulmonary Alveolar Microlithiasis
Pulmonary Alveolar Microlithiasis 		0.780 GeneticVariation disease BEFREE SLC34A2 Gene mutation of pulmonary alveolar microlithiasis: report of four cases and review of literatures. 23164546 2013
CUI: C0155912
Disease: Pulmonary Alveolar Microlithiasis
Pulmonary Alveolar Microlithiasis 		0.780 GeneticVariation disease BEFREE We present two cases of pulmonary alveolar microlithiasis with different mutations in the SLC34A2 gene that have not been previously described, and a review of the literature. 22941890 2012
CUI: C0155912
Disease: Pulmonary Alveolar Microlithiasis
Pulmonary Alveolar Microlithiasis 		0.780 GermlineCausalMutation disease ORPHANET A frame-shift mutation in the SLC34A2 gene in three patients with pulmonary alveolar microlithiasis in an inbred family. 20046000 2010
CUI: C0155912
Disease: Pulmonary Alveolar Microlithiasis
Pulmonary Alveolar Microlithiasis 		0.780 GeneticVariation disease BEFREE A case of pulmonary alveolar microlithiasis with an intragenetic deletion in SLC34A2 detected by a genome-wide SNP study. 19329736 2009
CUI: C0155912
Disease: Pulmonary Alveolar Microlithiasis
Pulmonary Alveolar Microlithiasis 		0.780 GeneticVariation disease BEFREE Mutations in the SLC34A2 gene that abolish normal gene function cause pulmonary alveolar microlithiasis. 17095743 2007
CUI: C0155912
Disease: Pulmonary Alveolar Microlithiasis
Pulmonary Alveolar Microlithiasis 		0.780 GeneticVariation disease BEFREE Mutations in SLC34A2 cause pulmonary alveolar microlithiasis and are possibly associated with testicular microlithiasis. 16960801 2006
CUI: C0155912
Disease: Pulmonary Alveolar Microlithiasis
Pulmonary Alveolar Microlithiasis 		0.780 GeneticVariation disease UNIPROT Mutations in SLC34A2 cause pulmonary alveolar microlithiasis and are possibly associated with testicular microlithiasis. 16960801 2006
CUI: C0155912
Disease: Pulmonary Alveolar Microlithiasis
Pulmonary Alveolar Microlithiasis 		0.780 Biomarker disease GENOMICS_ENGLAND Inherited interstitial lung disease. 15331184 2004
CUI: C0155912
Disease: Pulmonary Alveolar Microlithiasis
Pulmonary Alveolar Microlithiasis 		0.780 CausalMutation disease CLINVAR
CUI: C0155912
Disease: Pulmonary Alveolar Microlithiasis
Pulmonary Alveolar Microlithiasis 		0.780 Biomarker disease CTD_human
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.380 Biomarker disease BEFREE Correction to: The effects and mechanisms of SLC34A2 in tumorigenesis and progression of human non-small cell lung cancer. 30755199 2019
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.380 Biomarker disease BEFREE Our data suggested MEG3 was involved in stem cell-like state of LCCs and curbed migration and invasion through miR-650/SLC34A2 axis in NSCLC. 31585300 2019
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.380 Biomarker disease BEFREE The fusion gene SLC34A2-ROS1 (solute carrier family 34 member 2 and ROS proto-oncogene 1) plays an important role in non-small cell lung cancer (NSCLC) progression. 31118036 2019
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.380 GeneticVariation disease BEFREE Publicly available NSCLC cell lines harboring the ROS1 fusion gene are limited to only HCC78 cells carrying SLC34A2-ROS1. 29738763 2018
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.380 AlteredExpression disease BEFREE Dysregulation of SLC34A2 (NaPi2b) in tumors has attracted wide attention, but its expression and function in non-small cell lung cancer remains unclear. 28720066 2017
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.380 AlteredExpression disease BEFREE Hence, our data for the first time delineated that unusual expression of SLC34A2 was modulated by miR-410, and miR-410 might positivelycontribute to the tumorigenesis and development of NSCLC by down-regulating SLC34A2 and activating Wnt/β-catenin signaling pathway. 26910912 2016
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.380 AlteredExpression disease BEFREE Moreover, we found that expressions of SLC34A2 were reduced in six NSCLC cell lines for the first time. 26156586 2015
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.380 AlteredExpression disease BEFREE The expressed ROS1-SLC34A2 and CCDC6-RET gene fusions from the NSCLC cell lines HCC78 and LC-2/ad, respectively, were accurately detected by the novel assay. 25384172 2015
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.380 Biomarker disease CTD_human We selected NSCLC cell lines--A549 (KRAS G12S), NCI-H3255 (EGFR L858R), NCI-H3122 (EML4-ALK E13;A20), and HCC78 (SLC34A2-ROS1)-to evaluate the antiproliferative effects of submicromolar concentrations of the multitargeted TKIs imatinib, sorafenib, erlotinib, and crizotinib. 22617245 2012
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.380 Biomarker disease CTD_human Identifying and targeting ROS1 gene fusions in non-small cell lung cancer. 22919003 2012
CUI: C0013221
Disease: Drug toxicity
Drug toxicity 		0.300 Biomarker group CTD_human Prediction of nephrotoxicant action and identification of candidate toxicity-related biomarkers. 15805072 2005