|
Malignant mesothelioma
|
0.310 |
AlteredExpression
|
disease |
BEFREE |
Podoplanin is a type I transmembrane sialomucin-like glycoprotein that is highly expressed in malignant mesothelioma.
|
30801908 |
2019 |
|
Malignant mesothelioma
|
0.310 |
Biomarker
|
disease |
CTD_human |
Two cases of malignant peritoneal mesothelioma without asbestos exposure: cytologic and immunohistochemical features.
|
22784439 |
2013 |
|
Peritoneal Neoplasms
|
0.300 |
Biomarker
|
group |
CTD_human |
Two cases of malignant peritoneal mesothelioma without asbestos exposure: cytologic and immunohistochemical features.
|
22784439 |
2013 |
|
Carcinomatosis of peritoneal cavity
|
0.300 |
Biomarker
|
disease |
CTD_human |
Two cases of malignant peritoneal mesothelioma without asbestos exposure: cytologic and immunohistochemical features.
|
22784439 |
2013 |
|
Respiratory Distress Syndrome, Adult
|
0.210 |
Biomarker
|
disease |
BEFREE |
Therefore the purpose of this study was to establish the role of CLEC-2 and its ligand podoplanin in a mouse model of ARDS.
|
28839100 |
2017 |
|
Respiratory Distress Syndrome, Adult
|
0.210 |
Biomarker
|
disease |
RGD |
Low tidal volume reduces epithelial and endothelial injury in acid-injured rat lungs.
|
11790662 |
2002 |
|
Albuminuria
|
0.200 |
Biomarker
|
phenotype |
RGD |
Albuminuria developed starting at 6 wk of age and coincided with focal and segmental loss of podoplanin, increased expression of desmin, entrapment of albumin in affected podocytes, and focal and segmental foot process effacement at the ultrastructural level.
|
18199599 |
2008 |
|
Inflammation
|
0.200 |
Biomarker
|
phenotype |
RGD |
Coexpression of RTI40 with alveolar epithelial type II cell proteins in lungs following injury: identification of alveolar intermediate cell types.
|
15849211 |
2005 |
|
Hyperoxia
|
0.200 |
Biomarker
|
phenotype |
RGD |
Protein nitration in rat lungs during hyperoxia exposure: a possible role of myeloperoxidase.
|
12922978 |
2003 |
|
Oligohydramnios
|
0.200 |
Biomarker
|
phenotype |
RGD |
Effects of oligohydramnios on lung growth and maturation in the fetal rat.
|
11839536 |
2002 |
|
Nephrosis
|
0.200 |
Biomarker
|
disease |
RGD |
Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis.
|
9327748 |
1997 |
|
Pneumonia, Bacterial
|
0.200 |
Biomarker
|
group |
RGD |
A type I cell-specific protein is a biochemical marker of epithelial injury in a rat model of pneumonia.
|
7864138 |
1995 |
|
Malignant Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Podoplanin and ABCG2 expression in oral erythroplakia revisited: Potential evidence for cancer stem cells driving the process of field cancerization.
|
31300272 |
2020 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Because PDPN-positive CAFs are a hallmark of tumor malignancy, we assessed the regulation of PDPN and found that Src/Cas/PDPN signaling is mediated by RAMP3.
|
31754214 |
2020 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Because PDPN-positive CAFs are a hallmark of tumor malignancy, we assessed the regulation of PDPN and found that Src/Cas/PDPN signaling is mediated by RAMP3.
|
31754214 |
2020 |
|
Tumor Cell Invasion
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Areas of importance include central system regulators (Neurogenic Locus Notch Homolog Protein, miRNAs), proteins involved in tissue invasion (podoplanin, E-cadherin), and targets of existing and emerging therapeutics (PD-1, epidermal growth factor receptor).
|
31850970 |
2020 |
|
Primary malignant neoplasm
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Podoplanin and ABCG2 expression in oral erythroplakia revisited: Potential evidence for cancer stem cells driving the process of field cancerization.
|
31300272 |
2020 |
|
Primary malignant neoplasm
|
0.100 |
Biomarker
|
group |
BEFREE |
Because PDPN-positive CAFs are a hallmark of tumor malignancy, we assessed the regulation of PDPN and found that Src/Cas/PDPN signaling is mediated by RAMP3.
|
31754214 |
2020 |
|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Blocking CLEC-2-podoplanin interaction may be a novel therapeutic strategy in patients with podoplanin-expressing cancer.
|
31808911 |
2019 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Podoplanin expression is a prognostic biomarker but may be dispensable for the malignancy of glioblastoma.
|
30418623 |
2019 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Furthermore, we compared the MIB-1 labeling index of cancer cells in podoplanin (+) CAFs cases (n = 13) and podoplanin (-) CAFs cases (n = 14) using surgically resected adenocarcinoma specimens.
|
31319967 |
2019 |
|
Malignant Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
A strong podoplanin expression was observed in the membrane and cytoplasm of most lip tumor cells, and this was inversely associated with locoregional recurrence (p = 0.028) and with histopathological grade of malignancy (p = 0.026).
|
30770986 |
2019 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In this review, we discuss how Src and PDPN forge a path to tissue destruction, and how they can serve as targets for therapeutics to combat cancer and arthritis.
|
30077780 |
2019 |
|
Malignant Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
PDPN expression has been found in various human tumors and is considered to be a marker of cancer.
|
30654768 |
2019 |