GNA13, G protein subunit alpha 13, 10672

N. diseases: 46; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.040 Biomarker phenotype BEFREE To better understand how GNA13 contributes to tumorigenesis and tumor progression, we compared the entire transcriptome of PC3 prostate cancer cells with those cells in which GNA13 expression had been silenced. 31636124 2019
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.040 Biomarker phenotype BEFREE Taken together, these data indicate that GNA13 expression is a potential prognostic biomarker for tumor progression, and that interfering with GNA13-induced signaling provides a novel strategy to block TICs and drug resistance in HNSCCs. 29255247 2018
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.040 Biomarker phenotype BEFREE Gα12 and Gα13, encoded by GNA12 and GNA13, respectively, are referred to as the GEP oncogene and are implicated in tumor progression. 26804165 2016
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
0.040 Biomarker phenotype BEFREE Although mounting evidence suggests a role for G(12) proteins, G(α12) and G(α13), in tumor progression, a direct role of G(12) proteins has not been determined. 20044778 2010