KAT7, lysine acetyltransferase 7, 11143

N. diseases: 35; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.020 AlteredExpression group BEFREE Mutually exclusive expression of Hbo1 and ERα was observed in roughly half of the human breast tumors examined in the present study. 24125069 2013
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.020 Biomarker group BEFREE We also report that breast tumors expressing LMW-E have a higher proportion of CD44(hi)/CD24(lo) tumor cells as compared with tumors expressing only full-length cyclin E. In order to explore how LMW-E enriches cancer stem cells in breast tumors, we conducted a protein microarray analysis that identified the histone acetyltransferase (HAT) Hbo1 as a novel cyclin E/CDK2 substrate. 23955388 2013