CHI3L1, chitinase 3 like 1, 1116

N. diseases: 420; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.250 Biomarker group BEFREE Despite the presence of robust data suggesting the association of YKL-40 with variety of cardiovascular diseases (CV), there is no study up to date evaluating the role of YKL-40 on the long-term prognosis in patients with hypertension (HT). 31204510 2020
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.250 Biomarker group BEFREE We sought to explore the role of YKL-40 in endothelial dysfunction and hypertension in OSA patients. 31001555 2019
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.250 Biomarker group BEFREE In addition, a significant increase in serum levels of sCD36, PPAR-γ and YKL-40 was observed in patients with T2DM (>5 yr) with hypertension compared to healthy controls (P< 0.05). 29806605 2018
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.250 AlteredExpression group BEFREE Higher YKL-40 levels at baseline were positively associated with hypertension incidence among prehypertensive subjects. 28797750 2017
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.250 AlteredExpression group BEFREE YKL-40 levels were higher in women with hypertension, diabetes, and obesity and correlated modestly with high-density lipoprotein cholesterol, triglycerides, and hsCRP, but not with low-density lipoprotein cholesterol. 24958781 2014
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.250 Biomarker group RGD Gene expression profiles of major cytokines in the nucleus tractus solitarii of the spontaneously hypertensive rat. 18703386 2008