Cardiovascular Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Objective- APOA5 variants are strongly associated with hypertriglyceridemia, as well as increased risks of cardiovascular disease and acute pancreatitis.
|
30700132 |
2019 |
Cardiovascular Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The Association Between APOA5 Gene Polymorphisms and Plasma Lipids in the Turkish Cypriot Population: A Possible Biomarker for Preventing Cardiovascular Diseases.
|
29264753 |
2018 |
Cardiovascular Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
This study is a meta-analysis to determine APOA5 gene polymorphisms as risk factors for CVDs.
|
28252576 |
2017 |
Cardiovascular Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Population studies conducted in various countries have demonstrated an association between single nucleotide polymorphisms (SNPs) in ApoA5 and the increased risk to cardiovascular disease and metabolic syndrome (including diabetes and obesity).
|
23000317 |
2013 |
Cardiovascular Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Naturally occurring variants of the apolipoprotein A5 gene have been associated with increased triglyceride levels and have been found to confer risk for cardiovascular diseases.
|
20490738 |
2011 |
Cardiovascular Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Genetic variability at the APOA5 locus has also been associated with increased cardiovascular disease risk; however, this predisposition could be attenuated in the context of a prudent diet as traditionally consumed in the Mediterranean countries.
|
21209257 |
2011 |
Cardiovascular Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The aim of this study was to determine the associations between ApoA5 polymorphisms, plasma triglyceride concentrations and the presence of cardiovascular disease (CVD) in three ethnic origins.
|
20395964 |
2010 |
Cardiovascular Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Hypertriglyceridemia (HTG) is a well-established independent risk factor for cardiovascular disease and the influence of several genetic variants in genes related with triglyceride (TG) metabolism has been described, including LPL, APOA5 and APOE.
|
20429872 |
2010 |
Cardiovascular Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The T-1131C variant of the apolipoprotein A5 gene, associated with increased triglycerides, has been found to confer risk for cardiovascular diseases and metabolic syndrome.
|
18159097 |
2008 |
Cardiovascular Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Moreover, we address recent reports evaluating apolipoprotein A5 gene-environment interactions in relation to cardiovascular disease and its common risk factors.
|
18607181 |
2008 |
Cardiovascular Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Furthermore, the effects of variants in the APOA5 gene on carotid intima-media thickness (IMT) and cardiovascular disease (CVD) were examined.
|
17157483 |
2007 |
Cardiovascular Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Impact of APOA5/A4/C3 genetic polymorphisms on lipid variables and cardiovascular disease risk in French men.
|
16321685 |
2006 |
Cardiovascular Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The recently discovered apolipoprotein A5 ( APOA5 ) gene has been shown to be important in determining plasma triglyceride levels, a major cardiovascular disease risk factor.
|
15877284 |
2005 |
Cardiovascular Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The objective was to determine associations of the common apolipoprotein A5 gene (APOA5) -1131T-->C polymorphism with postprandial lipemic response and other cardiovascular disease risk factors in humans.
|
15447887 |
2004 |
Cardiovascular Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
We investigated associations of five APOA5 single-nucleotide polymorphisms (SNPs; -1131T>C, -3A>G, 56C>G IVS3+ 476G>A, and 1259T>C) with lipoprotein subfractions and CVD risk in 1,129 men and 1,262 women participating in the Framingham Heart Study.
|
15342688 |
2004 |
Cardiovascular Diseases
|
0.100 |
GeneticVariation
|
group |
LHGDN |
We investigated associations of five APOA5 single-nucleotide polymorphisms (SNPs; -1131T>C, -3A>G, 56C>G IVS3+ 476G>A, and 1259T>C) with lipoprotein subfractions and CVD risk in 1,129 men and 1,262 women participating in the Framingham Heart Study.
|
15342688 |
2004 |
Cardiovascular Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
These findings indicate that APOAV is an important determinant of plasma TG and lipoprotein cholesterol, and is potentially a risk factor for cardiovascular disease.
|
12671030 |
2003 |