Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.320 GeneticVariation disease BEFREE Modifying the role of serotonergic 5-HTTLPR and TPH2 variants on disulfiram treatment of cocaine addiction: a preliminary study. 22925276 2015
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.320 Biomarker disease PSYGENET We genotyped the SLC6A4 5-HTTLPR (rs4795541, rs25531) and TPH2 1125A>T (rs4290270) variants and evaluated their role in moderating disulfiram treatment for cocaine dependence. 22925276 2015
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.320 Biomarker disease PSYGENET This work suggests that variations in the TPH2 gene are not a risk factor for the development of cocaine dependence, but these findings require confirmation in larger, independent samples of cocaine-dependent and control subjects. 16759340 2006
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.320 GeneticVariation disease BEFREE Analysis of variations in the tryptophan hydroxylase-2 (TPH2) gene in cocaine dependence. 16759340 2006