Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032927
Disease: Precancerous Conditions
Precancerous Conditions
0.300 Biomarker group CTD_human Predominant Activation of JAK/STAT3 Pathway by Interleukin-6 Is Implicated in Hepatocarcinogenesis. 26297436 2016
CUI: C0282313
Disease: Condition, Preneoplastic
Condition, Preneoplastic
0.300 Biomarker phenotype CTD_human Predominant Activation of JAK/STAT3 Pathway by Interleukin-6 Is Implicated in Hepatocarcinogenesis. 26297436 2016
CUI: C0202202
Disease: Protein measurement
Protein measurement
0.100 GeneticVariation group GWASDB A genome-wide association study of circulating galectin-3. 23056639 2012
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.010 AlteredExpression disease BEFREE Although, the expression of key SOCS genes did not change to a large extent as a result of AD pathology, there were significantly increased levels of SOCS-2, SOCS-3 and CIS mRNA and increased protein levels of SOCS-4 and SOCS-7 in AD brains. 25286386 2016
CUI: C0007115
Disease: Malignant neoplasm of thyroid
Malignant neoplasm of thyroid
0.010 Biomarker disease BEFREE On investigating the mechanisms involved in IL-23 mediated migration and invasion, we observed that miR-25 promotes the migration and invasion of thyroid cancer cells by directly binding to the 3'-UTR of SOCS4 that leads to the inhibition of SOCS4. 26437444 2016
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma
0.010 Biomarker disease BEFREE On investigating the mechanisms involved in IL-23 mediated migration and invasion, we observed that miR-25 promotes the migration and invasion of thyroid cancer cells by directly binding to the 3'-UTR of SOCS4 that leads to the inhibition of SOCS4. 26437444 2016
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.010 GeneticVariation group BEFREE A missense mutation underlies defective SOCS4 function in a family with autoimmunity. 25639832 2015
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.010 Biomarker disease BEFREE Suppressor of cytokine signaling 4 detected as a novel gastric cancer suppressor gene using double combination array analysis. 22127425 2012
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma
0.010 Biomarker disease BEFREE Suppressor of cytokine signaling 4 detected as a novel gastric cancer suppressor gene using double combination array analysis. 22127425 2012
CUI: C0013884
Disease: Filarial Elephantiases
Filarial Elephantiases
0.010 AlteredExpression disease BEFREE Our data therefore indicate that the impaired Th1 responses observed in patent lymphatic filariasis are associated with decreased expression of T-bet, SOCS-1, SOCS-5, and SOCS-7 and increased expression of SOCS-3 in T cells. 15908366 2005