|
Dermatitis, Atopic
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
ICOSL increased the proliferation and expression of CCR4 and CCR10, and of interleukin (IL)-22 in AD PBMCs.
|
31090221 |
2020 |
|
Dermatitis, Atopic
|
0.100 |
Biomarker
|
disease |
BEFREE |
Collectively, CCR4 antagonists may be a promising approach for treating AD.
|
30551395 |
2019 |
|
Dermatitis, Atopic
|
0.100 |
Biomarker
|
disease |
BEFREE |
Ccr8- and Ccl8-deficient mice had markedly less eosinophilic inflammation than wild-type or Ccr4-deficient mice in a model of chronic atopic dermatitis.
|
21217759 |
2011 |
|
Dermatitis, Atopic
|
0.100 |
Biomarker
|
disease |
BEFREE |
Furthermore, when SNP-SNP interaction effects were analysed for these two genes, we found significant evidence for epistatic interactions between SNPs within each of the two genes but no evidence for a gene-gene interaction, suggesting that variation in or near both the CCR4 and the NFKB1 genes might individually contribute to AD pathogenesis.
|
17117949 |
2006 |
|
Dermatitis, Atopic
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
CXCR4 and CCR4 are the major chemokine receptor genes expressed in the giant papillae of AKC with atopic dermatitis and/or asthma.
|
15788997 |
2005 |
|
Dermatitis, Atopic
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
C1014T SNP of CCR4 does not appear to be associated with susceptibility to atopic dermatitis in Japanese patients.
|
15202833 |
2004 |
|
Dermatitis, Atopic
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The purpose of this study was to examine the expression and distribution of TARC and CCR4 mRNAs in samples of AD (n=15, acute lesions 8, chronic lesions 7) and normal skin (n=6).
|
12598706 |
2003 |
|
Dermatitis, Atopic
|
0.100 |
Biomarker
|
disease |
LHGDN |
Preferential expression of T(h)2-type chemokine and its receptor in atopic dermatitis.
|
12456591 |
2002 |
|
Dermatitis, Atopic
|
0.100 |
Biomarker
|
disease |
BEFREE |
The present study demonstrates that CCR4 contributes strongly to the immunopathogenesis of canine AD.
|
12459162 |
2002 |
|
Dermatitis, Atopic
|
0.100 |
Biomarker
|
disease |
BEFREE |
We observed that CCR4-expressing memory CD4+ T cells in the blood were more increased in AD patients as compared with normal patients, whereas CXCR3-expressing memory CD4+ T cells were present in a lower frequency in AD than seen in normal patients.
|
11037980 |
2000 |