CCR4, C-C motif chemokine receptor 4, 1233

N. diseases: 168; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
0.040 Biomarker disease BEFREE Finally, we discuss the therapeutic potential of newly developed CCR4 antagonists and a humanized anti-CCR4 antibody for treatment of MS. 29099057 2017
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
0.040 AlteredExpression disease BEFREE Activation of CCR4 by CKLF1 plays an important role in diseases such as asthma and multiple sclerosis. 20099827 2010
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
0.040 AlteredExpression disease BEFREE An important therapeutic effect of IFN-beta treatment may be the normalization of a decreased Th2-related CD4(+) T-cell CCR4 expression in MS patients. 16867161 2006
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
0.040 AlteredExpression disease BEFREE Similarly, both proinflammatory type (CCR1, CCR5) and immunomodulatory type (CCR4, CCR8) chemokine receptors were differentially expressed in the MS brain. 11086101 2000