COL1A1, collagen type I alpha 1 chain, 1277

N. diseases: 487; N. variants: 337
Disease: Keloid ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022548
Disease: Keloid
Keloid 		0.320 AlteredExpression disease BEFREE Following miR-96 antagomir treatment, a reduction in the mRNA and protein expression levels of collagen type I α 1 chain and collagen type 3 α 1 chain within keloid OC tissues was observed. 30651862 2019
CUI: C0022548
Disease: Keloid
Keloid 		0.320 Biomarker disease CTD_human Comparative proteomic analysis between normal skin and keloid scar. 20128793 2010
CUI: C0022548
Disease: Keloid
Keloid 		0.320 AlteredExpression disease BEFREE These data indicate that the rate of gene transcription of alpha 1(I) procollagen is increased in both hypertrophic scars and keloids, but only keloids exhibit increased steady-state levels of alpha 1(I) procollagen mRNA and concurrent increases in type I collagen. 8412102 1993