ADM, adrenomedullin, 133

N. diseases: 405; N. variants: 1
Disease: Glomerulonephritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis 		0.510 Biomarker disease RGD During GN a reduction of CLR and RAMP 2 + 3 expressions was detected on days 3, 7 and 14, while RAMP 1 rose.ADM mRNA decreased on days 3 and 7. 20431304 2010
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis 		0.510 Biomarker disease RGD Then, we made an anti-glomerular basement membrane (GBM) GN rat model and compared the AM expression and production in each glomeruli obtained from the control or m-PSL-treated anti-GBM GN rats. 16735801 2006
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis 		0.510 Biomarker disease CTD_human Renal AM level and its mRNA expression were increased in rats with GN compared with controls (Peptide Cortex: +69%; Medulla: +82%; mRNA Cortex: +25%). 15680492 2005
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis 		0.510 Biomarker disease CTD_human These results suggest that mycophenolate mofetil suppresses the renal damage in rats with autoimmune glomerulonephritis and renal adrenomedullin may participate in the pathophysiology of autoimmune glomerulonephritis. 15063164 2004
CUI: C0017658
Disease: Glomerulonephritis
Glomerulonephritis 		0.510 Biomarker disease BEFREE Considering the antiproliferative and proapoptotic effects of AM, its action on mesangial cells may be related to the amelioration of glomerulonephritis. 15619030 2004