ADORA2A, adenosine A2a receptor, 135

N. diseases: 213; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.370 GeneticVariation disease BEFREE The objective of this study was to examine the relationship between adenosine A2A receptor (<i>ADORA2A</i>) single nucleotide polymorphisms and schizophrenia in the North Chinese Han population. 31695381 2019
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.370 AlteredExpression disease BEFREE Reduced striatal adenosine A2A receptor levels define a molecular subgroup in schizophrenia. 24433848 2014
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.370 Biomarker disease PSYGENET Reduced striatal adenosine A2A receptor levels define a molecular subgroup in schizophrenia. 24433848 2014
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.370 Biomarker disease BEFREE The upregulation of several of these genes, IFITM1, IFITM2, IFITM3, APOL1 (Apolipoprotein L1), ADORA2A (adenosine receptor 2A), IGFBP4 and CD163 were validated in the schizophrenia subjects using data from the SNCID database and with quantitative RT-PCR. 24169640 2013
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.370 Biomarker disease PSYGENET Therefore, the current study investigated a possible relationship between peripheral adenosine A2A receptor (ADORA2A) and sensory gating indices (P50 measures) in medication-free schizophrenia (n=31) and healthy (n=21) groups. 22705363 2012
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.370 Biomarker disease BEFREE Therefore, the current study investigated a possible relationship between peripheral adenosine A2A receptor (ADORA2A) and sensory gating indices (P50 measures) in medication-free schizophrenia (n=31) and healthy (n=21) groups. 22705363 2012
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.370 Biomarker disease PSYGENET These deficits were related to SNPs from 16 genes, several previously associated with schizophrenia risk and/or involved in normal central nervous system development, including AKT, PI3K, SLC6A4, DRD2, CHRM2, and ADORA2A. 20691427 2010
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.370 Biomarker disease PSYGENET Our findings suggest that it is unlikely that the A2aAR 1976T > C polymorphism plays a major role in the pathogenesis of PD, schizophrenia, or antipsychotic-induced tardive dyskinesia in the Chinese population. 15719154 2005
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.370 GeneticVariation disease BEFREE The onset age of schizophrenia and tardive dyskinesia (evaluated with Abnormal Involuntary Movements Scale) were similar within the three A2aAR genotypic groups. 15719154 2005
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.370 GeneticVariation disease BEFREE Mapping of the human adenosine A2a receptor gene: relationship to potential schizophrenia loci on chromosome 22q and exclusion from the CATCH 22 region. 9050917 1997
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.370 GeneticVariation disease BEFREE Human adenosine A2a receptor (A2aAR) gene: systematic mutation screening in patients with schizophrenia. 9029412 1996