Schizophrenia
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
The objective of this study was to examine the relationship between adenosine A2A receptor (<i>ADORA2A</i>) single nucleotide polymorphisms and schizophrenia in the North Chinese Han population.
|
31695381 |
2019 |
Schizophrenia
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
Reduced striatal adenosine A2A receptor levels define a molecular subgroup in schizophrenia.
|
24433848 |
2014 |
Schizophrenia
|
0.370 |
Biomarker
|
disease |
PSYGENET |
Reduced striatal adenosine A2A receptor levels define a molecular subgroup in schizophrenia.
|
24433848 |
2014 |
Schizophrenia
|
0.370 |
Biomarker
|
disease |
BEFREE |
The upregulation of several of these genes, IFITM1, IFITM2, IFITM3, APOL1 (Apolipoprotein L1), ADORA2A (adenosine receptor 2A), IGFBP4 and CD163 were validated in the schizophrenia subjects using data from the SNCID database and with quantitative RT-PCR.
|
24169640 |
2013 |
Schizophrenia
|
0.370 |
Biomarker
|
disease |
PSYGENET |
Therefore, the current study investigated a possible relationship between peripheral adenosine A2A receptor (ADORA2A) and sensory gating indices (P50 measures) in medication-free schizophrenia (n=31) and healthy (n=21) groups.
|
22705363 |
2012 |
Schizophrenia
|
0.370 |
Biomarker
|
disease |
BEFREE |
Therefore, the current study investigated a possible relationship between peripheral adenosine A2A receptor (ADORA2A) and sensory gating indices (P50 measures) in medication-free schizophrenia (n=31) and healthy (n=21) groups.
|
22705363 |
2012 |
Schizophrenia
|
0.370 |
Biomarker
|
disease |
PSYGENET |
These deficits were related to SNPs from 16 genes, several previously associated with schizophrenia risk and/or involved in normal central nervous system development, including AKT, PI3K, SLC6A4, DRD2, CHRM2, and ADORA2A.
|
20691427 |
2010 |
Schizophrenia
|
0.370 |
Biomarker
|
disease |
PSYGENET |
Our findings suggest that it is unlikely that the A2aAR 1976T > C polymorphism plays a major role in the pathogenesis of PD, schizophrenia, or antipsychotic-induced tardive dyskinesia in the Chinese population.
|
15719154 |
2005 |
Schizophrenia
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
The onset age of schizophrenia and tardive dyskinesia (evaluated with Abnormal Involuntary Movements Scale) were similar within the three A2aAR genotypic groups.
|
15719154 |
2005 |
Schizophrenia
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
Mapping of the human adenosine A2a receptor gene: relationship to potential schizophrenia loci on chromosome 22q and exclusion from the CATCH 22 region.
|
9050917 |
1997 |
Schizophrenia
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
Human adenosine A2a receptor (A2aAR) gene: systematic mutation screening in patients with schizophrenia.
|
9029412 |
1996 |