|
Reperfusion Injury
|
0.500 |
Therapeutic
|
disease |
CTD_human |
Adenosine A2A and A2B Receptor Substantially Attenuate Ischemia/Reperfusion Injury in Septic rat Hearts.
|
27757725 |
2016 |
|
Reperfusion Injury
|
0.500 |
Biomarker
|
disease |
RGD |
Adenosine A2A activation attenuates nontransplantation lung reperfusion injury.
|
17937935 |
2008 |
|
Anxiety Disorders
|
0.390 |
Biomarker
|
group |
BEFREE |
Altogether, the present findings suggested that the ADORA2A gene and the interaction of ADORA2A and DRD2 genes may play a role in anxiety disorders in children and adolescents with ADHD.
|
30946941 |
2019 |
|
Anxiety Disorders
|
0.390 |
Biomarker
|
group |
BEFREE |
CYP1A2 is responsible for the majority of the metabolism of caffeine, and ADORA2A has been linked to caffeine-induced anxiety.
|
30248915 |
2018 |
|
Anxiety Disorders
|
0.390 |
GeneticVariation
|
group |
BEFREE |
Here, it was investigated whether the adenosine 2 A receptor gene (ADORA2A) 1976T/C (rs5751876) variant - previously associated with anxiety disorders and anxiety-related phenotypes as well as general attentional efficiency -was involved in the regulation of this network.
|
27262510 |
2016 |
|
Anxiety Disorders
|
0.390 |
Biomarker
|
group |
BEFREE |
The present results point to an impaired ability to selectively process very early information and to gate irrelevant sensory information, respectively, in female ADORA2A 1976TT homozygotes in response to caffeine, providing further evidence for the adenosinergic system to be involved in the pathogenesis of anxiety.
|
22940476 |
2013 |
|
Anxiety Disorders
|
0.390 |
GeneticVariation
|
group |
BEFREE |
Our data provide further support for an important role of ADORA2A variants in the pathogenesis of anxiety disorders and anxious personality reflecting their potential as basic susceptibility factors.
|
20334879 |
2010 |
|
Anxiety Disorders
|
0.390 |
GeneticVariation
|
group |
BEFREE |
In addition, association of ADORA2A variants with anxiety was replicated for individuals with ASD.
|
19565319 |
2010 |
|
Anxiety Disorders
|
0.390 |
GeneticVariation
|
group |
BEFREE |
Apart from the almost completely linked ADORA2A SNP rs3761422, no other of eight ADORA2A and seven ADORA1 SNPs studied were found to be clearly associated with effects of caffeine on anxiety, alertness, or headache.
|
20520601 |
2010 |
|
Anxiety Disorders
|
0.390 |
Biomarker
|
group |
CTD_human |
Genetics of caffeine consumption and responses to caffeine.
|
20532872 |
2010 |
|
Anxiety Disorders
|
0.390 |
Biomarker
|
group |
CTD_human |
Caffeine-induced anxiety (VAS) was also associated with two-loci interactions of selected ADORA2A and DRD2 polymorphisms.
|
18305461 |
2008 |
|
Anxiety Disorders
|
0.390 |
GeneticVariation
|
group |
BEFREE |
Caffeine-induced anxiety (VAS) was also associated with two-loci interactions of selected ADORA2A and DRD2 polymorphisms.
|
18305461 |
2008 |
|
Anxiety Disorders
|
0.390 |
GeneticVariation
|
group |
BEFREE |
Interindividual variation in anxiety response to amphetamine: possible role for adenosine A2A receptor gene variants.
|
16118787 |
2005 |
|
Anxiety Disorders
|
0.390 |
Biomarker
|
group |
CTD_human |
Interindividual variation in anxiety response to amphetamine: possible role for adenosine A2A receptor gene variants.
|
16118787 |
2005 |
|
Anxiety Disorders
|
0.390 |
Biomarker
|
group |
CTD_human |
Association between A2a receptor gene polymorphisms and caffeine-induced anxiety.
|
12825092 |
2003 |
|
Schizophrenia
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
The objective of this study was to examine the relationship between adenosine A2A receptor (<i>ADORA2A</i>) single nucleotide polymorphisms and schizophrenia in the North Chinese Han population.
|
31695381 |
2019 |
|
Panic Disorder
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
We found no association between ADORA2A polymorphism and PD.
|
26589317 |
2016 |
|
Schizophrenia
|
0.370 |
AlteredExpression
|
disease |
BEFREE |
Reduced striatal adenosine A2A receptor levels define a molecular subgroup in schizophrenia.
|
24433848 |
2014 |
|
Schizophrenia
|
0.370 |
Biomarker
|
disease |
PSYGENET |
Reduced striatal adenosine A2A receptor levels define a molecular subgroup in schizophrenia.
|
24433848 |
2014 |
|
Panic Disorder
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
The complex pathogenesis of anxiety and panic disorder in particular has been suggested to be influenced by genetic factors such as the adenosine A2A receptor gene (ADORA2A) 1976T>C polymorphism (rs5751876) as well as neuropsychological factors such as early information processing deficits.
|
22940476 |
2013 |
|
Schizophrenia
|
0.370 |
Biomarker
|
disease |
BEFREE |
The upregulation of several of these genes, IFITM1, IFITM2, IFITM3, APOL1 (Apolipoprotein L1), ADORA2A (adenosine receptor 2A), IGFBP4 and CD163 were validated in the schizophrenia subjects using data from the SNCID database and with quantitative RT-PCR.
|
24169640 |
2013 |
|
Panic Disorder
|
0.370 |
Biomarker
|
disease |
BEFREE |
We suggest that it is worth pursuing SLC6A4 in nonbladder PD, and ADORA2A and TMEM16B in bladder PD.
|
23018769 |
2012 |
|
Schizophrenia
|
0.370 |
Biomarker
|
disease |
PSYGENET |
Therefore, the current study investigated a possible relationship between peripheral adenosine A2A receptor (ADORA2A) and sensory gating indices (P50 measures) in medication-free schizophrenia (n=31) and healthy (n=21) groups.
|
22705363 |
2012 |
|
Schizophrenia
|
0.370 |
Biomarker
|
disease |
BEFREE |
Therefore, the current study investigated a possible relationship between peripheral adenosine A2A receptor (ADORA2A) and sensory gating indices (P50 measures) in medication-free schizophrenia (n=31) and healthy (n=21) groups.
|
22705363 |
2012 |
|
Panic Disorder
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
The adenosine A(2A) receptor gene (ADORA2A) is associated with panic disorder and is located on chromosome 22q11.23.
|
19565319 |
2010 |