KLF14, Kruppel like factor 14, 136259

N. diseases: 39; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.040 Biomarker disease BEFREE In addition, gypenosides (GP), a KLF14 activator, delayed the development of atherosclerosis in apolipoprotein E deficient (apoE<sup>-/-</sup>) mice. 31518965 2019
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.040 Biomarker disease BEFREE This review was designed to help understand the roles of KLF14 in the pathogenesis of atherosclerosis and define KLF14 as a potential disease biomarker and a novel therapeutic target in CVD. 28641818 2017
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.040 Biomarker disease BEFREE The present study was designed to investigate both in vivo and in vitro the impact of KLF14 on chronic inflammatory responses and atherosclerosis. 27923151 2017
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.040 Biomarker disease BEFREE Together, these results provide comprehensive insight into the KLF14-dependent regulation of HDL-C and subsequent atherosclerosis and indicate that interventions that target the KLF14 pathway should be further explored for the treatment of atherosclerosis. 26368306 2015