KLF14, Kruppel like factor 14, 136259

N. diseases: 39; N. variants: 2
Disease: Metabolic Syndrome X ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.030 Biomarker disease BEFREE Of particular interest are the genes being related to MetS (binary) in this study, but not to any of the MetS components in past studies, such as <i>WDR48, KLF14, NAADL1, GADD45G,</i> and <i>OR5R1,</i> as well as the two loci that have been associated with all five MetS components in past studies, <i>SNX10</i> and <i>C5orf67.</i> A pathway analysis of the 93 independent loci showed the immune system, transportation of small molecules, and metabolism to be enriched. 31589552 2019
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.030 GeneticVariation disease BEFREE Germline deletion of Krüppel-like factor 14 does not increase risk of diet induced metabolic syndrome in male C57BL/6 mice. 28962896 2017
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.030 GeneticVariation disease BEFREE Recent genome-wide association studies have revealed that variations near the gene locus encoding the transcription factor Krüppel-like factor 14 (KLF14) are strongly associated with HDL cholesterol (HDL-C) levels, metabolic syndrome, and coronary heart disease. 26368306 2015