Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.360 Biomarker group BEFREE Corticotropin-releasing factor binds with high affinity to CRF receptor 1 (CRFR1) and is implicated in stress-related mood disorders such as anxiety and depression. 30499109 2019
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.360 GeneticVariation group BEFREE Influence of CRHR1 Polymorphisms and Childhood Abuse on Suicide Attempts in Affective Disorders: A GxE Approach. 29755375 2018
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.360 Biomarker group PSYGENET Polymorphisms of CRHR1 and AVPR1b may modify susceptibility to mood disorders. 23962971 2013
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.360 Biomarker group BEFREE Our results suggest possible involvement of the AVPR1b and CRHR1 genes in the ethiology of psychotic features in the course of affective disorders, and possible involvement of CRHR1 gene in the ethiology of bipolar disorder. 24012103 2013
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.360 Biomarker group PSYGENET These translational data suggest that genetic variation in CRHR1 affects the risk for affective disorders by influencing the function of the neural circuit underlying AT and that differences in gene expression or the protein sequence involving exon 6 may be important. 23147386 2013
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.360 Biomarker group PSYGENET Our results suggest possible involvement of the AVPR1b and CRHR1 genes in the ethiology of psychotic features in the course of affective disorders, and possible involvement of CRHR1 gene in the ethiology of bipolar disorder. 24012103 2013
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.360 GeneticVariation group BEFREE Polymorphisms of CRHR1 and AVPR1b may modify susceptibility to mood disorders. 23962971 2013
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.360 Biomarker group BEFREE Deficient beta-arrestin-2-CRF(1) receptor interactions could contribute to the pathophysiology of affective disorders by inducing excessive CRF(1) receptor signaling. 17363685 2007
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.360 Biomarker group PSYGENET Deficient beta-arrestin-2-CRF(1) receptor interactions could contribute to the pathophysiology of affective disorders by inducing excessive CRF(1) receptor signaling. 17363685 2007
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.360 Biomarker group BEFREE Corticotropin-releasing factor receptor antagonists in affective disorders and drug dependence-- an update. 16611089 2006
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.360 Biomarker group PSYGENET Corticotropin-releasing factor receptor antagonists in affective disorders and drug dependence-- an update. 16611089 2006