Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Identified predictors of 4-year golimumab discontinuation were patient's global and female gender in patients overall and in subgroups of PsA and ax-SpA patients, and patient's global and CRP in RA.
|
31358361 |
2020 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
However, patients who had a family history of RA and were ACPA positive showed significantly lower erythrocyte sedimentation rate, and C-reactive protein.
|
31620864 |
2020 |
Rheumatoid Arthritis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
In this observational study, patients with untreated RA at risk of inadequate response to MTX included those with a higher TJC and higher CRP, while a higher TJC was the only independent predictor of an inadequate response to csDMARDs other than MTX.
|
30482075 |
2020 |
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
However, Midkine presents a significantly higher diagnostic accuracy (AUC=0.939) in detecting RA activity than that offered by C reactive protein (CRP) or ESR.
|
31324694 |
2020 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
In the full cohort and in RA, baseline and/or 12-month bone mineral density (BMD) at multiple sites exerted inverse relationships with CRP and βCTX, and positive correlation with SOST.
|
31522318 |
2020 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Correlation between albumin to fibrinogen ratio, C-reactive protein to albumin ratio and Th17 cells in patients with rheumatoid arthritis.
|
31672633 |
2020 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
To compare the multi-biomarker disease activity (MBDA) score with the DAS28-CRP and CRP for predicting risk of radiographic progression in patients with rheumatoid arthritis.
|
30777458 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
The RA group had higher CRP (P = 0.006), were more likely to receive glucocorticoids (P<0.001), and experienced worse fatigue (P = 0.050).
|
31170172 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Multivariate regression analysis demonstrated significant correlations between GLSs and RA duration (p = 0.02), and GLSs and DAS28-CRP (p = 0.041).
|
31843000 |
2019 |
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
The increase of blood platelet, and CRP levels and decrease of blood albumin are probable risk factors for PN in RA patients.
|
30911944 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
In conclusion, IL-1β, IL-17A, CRP and biologics history would serve as potential markers for clinical response to ETN in RA patients.
|
31463666 |
2019 |
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
To investigate serum interleukin (IL)- 35 levels in patients with rheumatoid arthritis (RA) and to describe the association between serum IL-35 levels and clinical parameters: erythrocyte sedimentation rate (ESR), C reactive protein (CRP), global health on Visual Analog Scale, Disease Activity Score in 28 joints based on ESR (DAS28-ESR), rheumatoid factor (RF) and anticyclic citrullinated peptide antibodies (ACPAs).
|
30659089 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Fifty-two percent developed RA.Foot tenosynovitis was predictive (OR 2.55, 95% CI 1.01-6.43), independent of BME and synovitis (OR 3.29, 95% CI 1.03-10.53), but not independent of CRP and number of swollen joints (OR 2.14, 95% CI 0.77-5.95).
|
30764871 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
The plasma VEGF levels and VEGF expressions in CD4+ T, CD8+ T, and Treg subsets positively correlated with SDAI and CRP in RA patients.
|
31820713 |
2019 |
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
At baseline, patients with established RA had a median DAS28 of 4.8 (3.2-8.3) and, compared to healthy controls, had higher plasma levels of CRP (p < 0.0001), FXIII (p = 0.017) and F1+2 (p < 0.0001).
|
31654331 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Of 5376 patients with RA enrolled in the Korean observational study network for arthritis (KORONA) registry, 400 patients with disease duration of <2 years who had Clinical Disease Activity Index (CDAI) score of >2.8 at baseline, biologic-naïve, and erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) drawn at both baseline and 2-year follow-up visits were identified.
|
30677239 |
2019 |
Rheumatoid Arthritis
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Furthermore, we found that ESR and LDL-C levels could exhibit a linear association with the risk of comorbid stroke while CRP level had a nonlinearity association with stroke risk among RA patients.
|
30729371 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
The percentage of CD4⁺PD-1⁺CXCR5⁺ Tfh cells was correlated positively with the values of erythrocyte sedimentation rate (ESR) (r=0.968, P<0.001), rheumatoid factor (RF) (r=0.962, P<0.001), C-reactive protein (CRP) (r=0.953, P<0.001), and anti-cyclic citrullinated peptide antibodies (ACPA) (r=0.966, P<0.001), and the level of serum interleukin (IL)-21 in RA patients showed positive correlation with ESR (r=0.982, P<0.001), RF (r=0.959, P<0.001), CRP (r=0.951, P<0.001), and ACPA (r=0.971, P<0.001) as well.
|
31019190 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
The aim of our study was to evaluate the effects of intravenous administration of autologous bone marrow-derived MSCs on the immunological, clinical and para-clinical factors such as regulatory T cells, Th17 cells, CD8+ T cells, CD4+ T cells, disease activity score 28-erythrocyte sedimentation rate (DAS28-ESR), visual analogue scale (VAS), ESR, C-reactive protein (CRP), rheumatoid factor (RF), and anti-cyclic citrullinated peptide (anti-CCP) antibodies in patients with refractory RA.
|
30551438 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
The human miR-34a, increased in peripheral blood mononuclear cells (PBMCs) and CD4<sup>+</sup> T cells from rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) patients, displayed a positive correlation with some serum markers of inflammation including rheumatoid factor (RF), anti-streptolysin antibody (ASO), erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) as well as Th17 signature gene RORγt, but inversely correlated with the mRNA expression levels of FOXP3.
|
31130368 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
ESR and CRP were the most sensitive acute-phase reactants in females with RA and there was a correlation between ESR and CRP values in RA patients.
|
31451934 |
2019 |
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Manual job and absence of medical insurance predicted leaving the labour force before official retirement age due to RA.Key Points• A decline in work capacity is an important outcome of the disease.• Attention has not been paid to this issue in India.• Potential predictors for work capacity impairment in RA include: educational level, monthly income, job type, disease activity, CRP, physical function.• Targeting the predictors may result in reducing work capacity impairment in RA.
|
31838638 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
In addition, disease activity markers of RA (DAS28, CRP, ESR) and specific antibodies (RF) were monitored in the RA-CP group.
|
29589156 |
2019 |
Rheumatoid Arthritis
|
0.600 |
Biomarker
|
disease |
BEFREE |
Linear regression modeled the effect of biologic exposure on changes in disease activity (Disease Activity Score-28 with C-reactive protein [DAS28-CRP]), functional status (modified Health Assessment Questionnaire [mHAQ]), and RA severity (Routine Assessment of Patient Index Data [RAPID3]).
|
31353421 |
2019 |
Rheumatoid Arthritis
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
We aimed to determine the association between PON-1L55M polymorphism and its effects on inflammatory markers such as anti-cytroline circulated-peptide (CCP)-antibodies, C-reactive protein (CRP), neopterin serum concentration, arylesterase (ARE) and butyrylcholinesterase (BuChE) activities and total-antioxidant-capacity (TAC) level with the activity of disease in RA patients.
|
30506510 |
2019 |