Diabetes Mellitus, Insulin-Dependent
|
0.400 |
Biomarker
|
disease |
BEFREE |
(2) Methods: In 398 newborns from the Danish Newborn Screening Biobank, we examined if whole blood iron (WB-Iron) content were associated with cytokines, adipokines, C-reactive protein (CRP), and mannose-binding lectin (MBL) in non-infected healthy neonates, and if these associations differed in newborns who later developed T1D (cases) (<i>n</i> = 199).
|
30836628 |
2019 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
Biomarker
|
disease |
BEFREE |
In the subsequent analysis of the relationship between CRP and type 1 diabetes mellitus (T1DM), the pooled result (OR 1.017145; 95% CI 0.9066489 to 1.14225; <i>P</i> = 0.909) supported that CRP levels cannot determine the risk of developing T1DM.
|
30619477 |
2018 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
CRP levels were higher in the T1D-EV+ group than in the T1D-EV- group, and higher in all diabetic children than in nondiabetic controls.
|
29320773 |
2018 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
In youth with T1D, glucose rate of disappearance correlated with free fatty acid at the 80-mU/m2/min phase (P = 0.005), markers of inflammation (IL-6; P = 0.012), high-sensitivity C-reactive protein (P = 0.001), and leptin (P = 0.008)], but not hemoglobin A1c.
|
30020457 |
2018 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
Biomarker
|
disease |
BEFREE |
Only in T1D boys serum UA was positively correlated with concentrations of subclinical inflammatory markers (CRP, IL-6, TNF-α), the indicators of renal function (albumin excretion rate, serum cystatin C level), blood pressure and negatively correlated with anti-inflammatory IL-10.
|
29527782 |
2018 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
Biomarker
|
disease |
BEFREE |
This study evaluated the association of four distinct dietary quality indices (Dietary Approaches to Stop Hypertension (DASH), Healthy Eating Index 2010 (HEI2010), modified KIDMED and Total Antioxidant Capacity (TAC)) with biomarkers of inflammation (C-reactive protein (CRP), fibrinogen and interleukin-6 (IL-6)) in a sample of 2520 youth with T1D participating in the SEARCH for Diabetes in Youth Study.
|
29198994 |
2018 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
Biomarker
|
disease |
BEFREE |
This study was based on a retrospective observational analysis from 2 July 2014 to 27 June 2016, which evaluated the occurrence of T1D and changes in glycemia and C-reactive protein (CRP) plasma concentrations in patients undergoing anti-PD-1 and/or anti-CTLA-4 treatment for melanoma at the Saint Louis Hospital.
|
29808365 |
2018 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Association between adherence to dietary recommendations and high-sensitivity C-reactive protein level in type 1 diabetes.
|
28237858 |
2017 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
Biomarker
|
disease |
BEFREE |
Non-HDL-cholesterol and C-reactive protein in children and adolescents with type 1 diabetes.
|
28222033 |
2017 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
Biomarker
|
disease |
BEFREE |
Comparisons between populations showed increased levels of haemoglobin A1c (HbA1c), C-reactive protein (CRP), nitric oxide (NO), glutamic acid decarboxylase and insulin and islet cell autoantibodies [glutamic acid decarboxylase autoantibodies (GADA), insulin autoantibodies (IAA) and islet cell cytoplasmic autoantibodies (ICA), respectively], interferon (IFN)-γ, tumour necrosis factor (TNF)-α, interleukin (IL)-1β, IL -10, IL -12, IL -17, C3d and sC5-9 in T1D-EV<sup>+</sup> versus T1D-EV<sup>-</sup> .
|
28640379 |
2017 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
Biomarker
|
disease |
BEFREE |
Univariate analysis in T1D showed RTL correlated (inversely) with age r=-0.27, p=0.0001, T1D duration r=-0.16, p=0.03, and pulse pressure (r=-0.15, p=0.04), but not with HbA1c, BP, renal function (serum creatinine, ACR, eGFR), lipids, insulin sensitivity, inflammation (CRP, CAMs) or oxidative stress (OxLDL, OxLDL/LDL-C, MPO, PON-1).
|
27329016 |
2016 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
Biomarker
|
disease |
BEFREE |
Furthermore, we identified 53 loci with significant effects in both CAD and at least 1 of low-density lipoprotein, high-density lipoprotein, triglycerides, type 2 diabetes mellitus, C-reactive protein, systolic blood pressure, and type 1 diabetes mellitus.
|
26487741 |
2016 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
Biomarker
|
disease |
BEFREE |
We measured the concentrations of oxidative/inflammatory biomarkers (urinary 15-isoprostane F(2t) [IsoP], α- and γ-tocopherol, tumor necrosis factor α [TNF-α], high-sensitivity C-reactive protein [hsCRP], white blood cell [WBC] count, fibrinogen, and adiponectin) thrice during 20 years of follow-up among 454 individuals with childhood-onset type 1 diabetes (mean baseline age, 28 years and diabetes duration, 19 years).
|
26114833 |
2015 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
Biomarker
|
disease |
BEFREE |
Type 1 diabetes mellitus (T1DM) is a pro-inflammatory state characterized by high C-reactive protein (CRP) levels.
|
22801596 |
2012 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The association between Lp-PLA(2) activity and CAD differs by CRP and haptoglobin genotype in this group of persons with type 1 diabetes and macroalbuminuria.
|
20368232 |
2010 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
Biomarker
|
disease |
CTD_human |
Antioxidant potential, paraoxonase 1, ceruloplasmin activity and C-reactive protein concentration in diabetic retinopathy.
|
20012460 |
2010 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We selected 46 variants: (1) eight variants known to alter circulating levels of inflammatory proteins, including those in the IL18, IL1RN, IL6R, MIF, PAI1 (also known as SERPINE1) and CRP genes; and (2) 38 variants known to predispose to autoimmune diseases, including type 1 diabetes.
|
18853133 |
2008 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
Biomarker
|
disease |
BEFREE |
The results suggest that maternal type 1 diabetes increases the foetal plasma LDL cholesterol and CRP concentration and thus might predispose the offspring to development of atherosclerosis.
|
18551710 |
2008 |
Diabetes Mellitus, Insulin-Dependent
|
0.400 |
Biomarker
|
disease |
BEFREE |
Brachial artery endothelium-dependent, flow-mediated dilation (BA-FMD) and carotid artery intima-media thickness (CA-IMT), as well as markers of systemic inflammation [C-reactive protein (CRP), fibrinogen, and orosomucoid], HbA(1C), LDL, HDL, and total cholesterol, were assessed in 86 children and adolescents with Type 1 diabetes (mean age and diabetes duration, 15 and 7 yr, respectively) between 2004 and 2006.
|
17906106 |
2007 |