CRP, C-reactive protein, 1401

N. diseases: 1483; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018799
Disease: Heart Diseases
Heart Diseases
0.380 Biomarker group BEFREE BMI >45 kg/m<sup>2</sup> was associated with higher prevalence of hypertension, systolic and diastolic blood pressure, C-reactive protein, waist circumference, body fat % and family history of heart diseases, enhancing the risk for the occurrence of cardiovascular diseases. 31791637 2020
CUI: C0018799
Disease: Heart Diseases
Heart Diseases
0.380 AlteredExpression group BEFREE Prognosis of myocardial infarction tends to be worse when serum C-reactive protein (CRP) level is high. miRNAs are also known to be involved in different pathogeneses of heart diseases such as myocardial infarction. 31063484 2019
CUI: C0018799
Disease: Heart Diseases
Heart Diseases
0.380 Biomarker group BEFREE The rich expression of antimicrobial peptides and its association with CRP support the idea that an inflammatory process is involved in the pathogenesis of acquired heart diseases. 30734265 2019
CUI: C0018799
Disease: Heart Diseases
Heart Diseases
0.380 Biomarker group BEFREE Statins have antiinflammatory effects and are known to decrease risk of cardiovascular events and to reduce serum levels of C-reactive protein (CRP), a widely studied biomarker and potential mediator of inflammation and heart disease. 24410968 2014
CUI: C0018799
Disease: Heart Diseases
Heart Diseases
0.380 GeneticVariation group BEFREE Genetic predisposition to high baseline CRP might account for a high risk of heart diseases. 22828776 2012
CUI: C0018799
Disease: Heart Diseases
Heart Diseases
0.380 Biomarker group BEFREE C-reactive protein promotes cardiac fibrosis and inflammation in angiotensin II-induced hypertensive cardiac disease. 20157054 2010
CUI: C0018799
Disease: Heart Diseases
Heart Diseases
0.380 Biomarker group CTD_human Elevation of C-reactive protein (CRP) levels in blood was recognized as one of the cardiac disease risk factors. 17388968 2007
CUI: C0018799
Disease: Heart Diseases
Heart Diseases
0.380 Biomarker group BEFREE The basic mechanisms responsible for this association are not clear; CRP may merely be a marker of inflammation with no specific role in the pathogenesis of cardiac disease or may directly modulate the disease process. 12237169 2002
CUI: C0018799
Disease: Heart Diseases
Heart Diseases
0.380 GeneticVariation group BEFREE Elevation of baseline C-reactive protein (CRP) is associated with increased risk of cardiac disease. 11857055 2002