|
Metabolic Syndrome X
|
0.400 |
Biomarker
|
disease |
BEFREE |
In comparison to controls, PE/E significantly increased systolic BP (MD = 8.3 mmHg, 95%CI 6.8 to 9.7), diastolic BP (MD = 6.8 mmHg, 95%CI 5.6 to 8.0), BMI (MD = 2.0 kg/m<sup>2</sup>; 95%CI 1.6 to 2.4), waist (MD = 4.3 cm, 95%CI 3.1 to 5.5), waist-to-hip ratio (MD = 0.02, 95%CI 0.01 to 0.03), weight (MD = 5.1 kg, 95%CI 2.2 to 7.9), total cholesterol (MD = 4.6 mg/dL, CI 1.5 to 7.7), LDL (MD = 4.6 mg/dL; 95%CI 0.2 to 8.9), triglycerides (MD = 7.7 mg/dL, 95%CI 3.6 to 11.7), glucose (MD = 2.6 mg/dL, 95%CI 1.2 to 4.0), insulin (MD = 19.1 pmol/L, 95%CI 11.9 to 26.2), HOMA-IR index (MD = 0.7, 95%CI 0.2 to 1.2), C reactive protein (MD = 0.05 mg/dL, 95%CI 0.01 to 0.09), and the risks of hypertension (RD = 0.24, 95%CI 0.15 to 0.33) and MetS (RD = 0.11, 95%CI 0.08 to 0.15).
|
31734276 |
2020 |
|
Metabolic Syndrome X
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Abnormal CRP levels were significantly associated with increased MDD and more strongly with increased rates of non-remission under antidepressants in SZ patients, independently of age, gender, psychotic symptomatology, functioning, tobacco smoking and metabolic syndrome.
|
31676465 |
2020 |
|
Metabolic Syndrome X
|
0.400 |
Biomarker
|
disease |
BEFREE |
Secondarily, cortisol stimulation will contribute to the development of central obesity which is known to facilitate the development of metabolic syndrome, including slightly increased levels of inflammatory biomarkers such as C-reactive protein and fibrinogen.
|
31177066 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
Biomarker
|
disease |
BEFREE |
Serum concentrations of IL-6, endothelin, leptin, and CRP were higher in the MS group, contrary to adiponectin concentration which was lower (p < 0.01).
|
28382609 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
Biomarker
|
disease |
BEFREE |
The concentrations of alanine aminotransferase (ALT), serum uric acid (SUA), low density lipoprotein (LDL), and C-reactive protein (CRP) were higher in the MetS children in comparison with non-MetS children (All p < 0.05), while the high-density lipoprotein (HDL) concentration was lower in MetS children.
|
31752150 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Obesity and metabolic syndrome are important risk factors for OA and also induce elevated CRP levels.
|
30248505 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
Biomarker
|
disease |
BEFREE |
To find out the CRP cutoff between MS and non-MS obesity, we performed ROC curve analyses: hs-CRP lower than 1.96 mg/l was the best predictor of simple obesity without MS (sensitivity = 66.7%; specificity = 66.7%; AUC = 0.7; p = .0002).
|
29392970 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Altogether, our data reveal a clear association between the presence of MetS, a greater number of MetS-components or CRP levels >2.5 mg/L with an increased Sig-PCa diagnosis and/or with aggressive features, suggesting that MetS and/or CRP levels might influence PCa pathophysiology.
|
30450757 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
Biomarker
|
disease |
BEFREE |
Here, the potential influence of systemic inflammation (assessed by serum high-sensitivity C-reactive protein [hs-CRP]) on hypertension remission will be investigated in a cohort of hypertensive patients with MetS.
|
31091356 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Captivity-induced PTSD, in particular chronic and delayed PTSD trajectories, was associated with elevated CRP levels and MetS, significantly so for MetS (P = .05).
|
28994516 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
Biomarker
|
disease |
BEFREE |
Currently, it is recommended that clinical assessment of male infertility and reproductive dysfunction in obese and MetS patients includes inflammation assessment (highly sensitive C-reactive protein), and appropriate advice and therapeutic options are incorporated in the management options.
|
31373727 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Moreover, metabolic syndrome and high serum levels of CRP were significantly associated with the risk of CDAD.
|
31688897 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
Biomarker
|
disease |
BEFREE |
At the end of the 5-year follow- up, compared with subjects without MS, hazard ratios and 95% confidence intervals for the different risks in subjects with MS were 1.86 (1.02-3.29) for myocardial infarction (MI), 1.39 (1.01-2.05) for stroke, 1.52 (1.02- 2.37) for CVD death, and 1.13 (0.62-2.58) for total death, after adjusting for age, gender, smoking, drinking, physical activity, uric acid, high-sensitivity C-reactive protein, dietary factors and carotid atherosclerosis status.
|
31826385 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
After adjustment, presence of metabolic syndrome was associated with higher IL-6 and CRP levels and lower CXCL8 and CCL5.
|
30916180 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The CRP level was strongly associated with VO<sub>2peak</sub> and the MetSyn, but not with FMD.
|
30935704 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
We previously found that blood C-reactive protein (CRP), interleukin-6 (IL-6), and leptin levels were predictors of current metabolic syndrome in schizophrenia.
|
31118157 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
Biomarker
|
disease |
BEFREE |
The objective of this study was to analyze the association between HDL-C subfractions and each metabolic syndrome component, homeostasis model assessment-estimated insulin resistance (HOMA-IR) and C-reactive protein (CRP).
|
29941395 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
Biomarker
|
disease |
BEFREE |
Cardiac myocyte injury and stress markers (troponin and natriuretic peptides), markers of renal function (glomeral filtration rate, cystatin-C), and inflammation markers/mediators (interleukin- 6, CRP) are promising biomarkers of patients with AF and MetS.
|
29022500 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
Biomarker
|
disease |
BEFREE |
In the multivariable analysis, plasma CRP concentration was associated with increased prevalence of hypertriglyceridaemia (OR 1.157, 95% CI 1.040 to 1.287, p=0.007), diabetes (OR 1.204, 95% CI 1.058 to 1.371, p=0.005) and metabolic syndrome (OR 1.228, 95% CI 1.112 to 1.357, p<0.001) after adjustment for socioeconomic and lifestyle characteristics.
|
31473619 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
Biomarker
|
disease |
BEFREE |
Correction to: Statin Therapy in Metabolic Syndrome and Hypertension Post-JUPITER: What is the Value of CRP?
|
30662999 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Researchers have identified the significance of CRP levels in predicting future sequelae of MetS such as ASCVD.
|
31229566 |
2019 |
|
Metabolic Syndrome X
|
0.400 |
Biomarker
|
disease |
BEFREE |
The upregulation of IFNγ and IL-6 and CRP suggests that autoinflammatory process may play a significant role in the pathogenesis of metabolic syndrome.
|
30383538 |
2018 |
|
Metabolic Syndrome X
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Significant associations were found between a higher rate of metabolic syndrome (OR = 0.10, 95% CI = 0.02-0.41) and high CRP levels.
|
29156363 |
2018 |
|
Metabolic Syndrome X
|
0.400 |
Biomarker
|
disease |
BEFREE |
MDD was associated with Metabolic syndrome (31.4 v. 20.2%; P = 0.006) but not with increased C-reactive protein.
|
29871707 |
2018 |
|
Metabolic Syndrome X
|
0.400 |
Biomarker
|
disease |
BEFREE |
Data of lower urinary tract symptoms, C-reactive protein (CRP), platelet distribution width (PDW), prostate-specific antigen (PSA), Gleason score, clinical stage, treatment methods, and progressive incidents were evaluated using logistic regression according to MetS diagnosis.
|
29948970 |
2018 |