ADRA1A, adrenoceptor alpha 1A, 148

N. diseases: 294; N. variants: 30
Disease: Bladder neck obstruction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005694
Disease: Bladder neck obstruction
Bladder neck obstruction 		0.210 Biomarker disease BEFREE We investigated the effects of silodosin, an α1A-adrenoceptor (AR) antagonist, on bladder function, especially on non-voiding contractions (NVCs), in a male rat model of bladder outlet obstruction (BOO) by evaluating cystometry (CMG) findings and bladder mechanosensitive single-unit afferent activities (SAAs), related with microcontractions, which may be similar with NVCs and to be of myogenic origin, in the rat model. 29508437 2018
CUI: C0005694
Disease: Bladder neck obstruction
Bladder neck obstruction 		0.210 Biomarker disease RGD Alpha1-adrenoceptor antagonists improve bladder storage function through reduction of afferent activity in rats with bladder outlet obstruction. 20886573 2011