ADRA1A, adrenoceptor alpha 1A, 148

N. diseases: 294; N. variants: 30
Disease: cocaine use ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3496069
Disease: cocaine use
cocaine use 		0.310 Biomarker disease PSYGENET We examined whether a functional variant of the ADRA1A gene (Cys to Arg at codon 347 in exon 2, Cys347Arg) may enhance treatment response through decreased stimulation of this α1A-adrenoceptor, since antagonists of this receptor show promise in reducing cocaine use. 23849431 2013
CUI: C3496069
Disease: cocaine use
cocaine use 		0.310 GeneticVariation disease BEFREE We examined whether a functional variant of the ADRA1A gene (Cys to Arg at codon 347 in exon 2, Cys347Arg) may enhance treatment response through decreased stimulation of this α1A-adrenoceptor, since antagonists of this receptor show promise in reducing cocaine use. 23849431 2013