ADRA2A, adrenoceptor alpha 2A, 150

N. diseases: 102; N. variants: 7
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.040 GeneticVariation disease BEFREE The association of ADRA2A single-nucleotide polymorphisms (SNPs) with obesity and/or type 2 diabetes (T2D) was investigated. 23526671 2013
CUI: C0028754
Disease: Obesity
Obesity 		0.040 Biomarker disease BEFREE The potential usefulness of such drugs may vary between individuals, depending on α(2A)-adrenoceptor genetics, sympathetic tone and concomitant pathological conditions, such as cardiovascular disease and obesity. 21418144 2011
CUI: C0028754
Disease: Obesity
Obesity 		0.040 GeneticVariation disease BEFREE Interactions were detected between ADRA2A C-1291G and ADRB2 Gln27-->Glu variants for obesity in African Americans and between ADRA2A C-1291G SNP and ADBR1 haplotype for obesity in whites. 17512307 2007
CUI: C0028754
Disease: Obesity
Obesity 		0.040 GeneticVariation disease BEFREE The objective of the current study was to examine the potential impact of a C right arrow G substitution at position -1291 of the alpha2A-adrenergic receptor gene (ADRA2A) promoter on obesity and estimates of insulin, glucose, and lipid metabolism as well as circulating hormones, including salivary cortisol in 284 unrelated Swedish men born in 1944. 11886485 2002