ADRA2A, adrenoceptor alpha 2A, 150

N. diseases: 102; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0424101
Disease: Inattention
Inattention
0.060 GeneticVariation phenotype BEFREE No significant association between the alpha-2A-adrenergic receptor gene and treatment response in combined or inattentive subtypes of attention-deficit hyperactivity disorder. 23824524 2013
CUI: C0424101
Disease: Inattention
Inattention
0.060 GeneticVariation phenotype BEFREE We have examined the effect of ADRA2A C-1291G on inattentive, hyperactive and aggressive behaviour in a population representative cohort of healthy schoolchildren, and possible interaction of genotype with family relations. 19922756 2010
CUI: C0424101
Disease: Inattention
Inattention
0.060 GeneticVariation phenotype BEFREE We extended to ADHD-I previous findings suggesting the influence of the G allele at the ADRA2A -1291 C > G polymorphism on the improvement of inattentive symptoms with methylphenidate in children with all ADHD subtypes. 18200436 2008
CUI: C0424101
Disease: Inattention
Inattention
0.060 Biomarker phenotype BEFREE Several molecular genetic investigations suggest a role for the adrenergic alpha2A receptor gene (ADRA2A) in attention-deficit/hyperactivity disorder (ADHD), especially in the inattentive dimension. 17283289 2007
CUI: C0424101
Disease: Inattention
Inattention
0.060 Biomarker phenotype BEFREE Our results suggest that the ADRA2A may be associated with ADHD-I, replicating previous findings from clinical samples that have suggested the importance of this gene for the dimension of inattention. 16806103 2006
CUI: C0424101
Disease: Inattention
Inattention
0.060 GeneticVariation phenotype BEFREE Although no association with either MspI allele was observed through the haplotype relative risk (HRR) analysis, effects of the ADRA2A gene on inattention and combined (inattention + hyperactivity/impulsivity) symptom scores were detected (U = 222.5, z = 2.19, P = 0.03; and U = 208.5, z = 2.32, P = 0.02, respectively). 12815749 2003