CXADR, CXADR Ig-like cell adhesion molecule, 1525

N. diseases: 305; N. variants: 1
Disease: Malignant Glioma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma 		0.020 AlteredExpression disease BEFREE Transduction of malignant glioma with adenovirus serotype 5 (Ad5) vectors is limited by the low levels of coxsackievirus and adenovirus receptor (CAR) on tumor cells. 17328684 2007
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma 		0.020 AlteredExpression disease BEFREE Strategies to further improve the efficacy of Ad5-gfa2(B)3-E1 for the treatment of malignant gliomas include the insertion of therapeutic genes in E3 or retargeting to receptors that are more abundantly expressed on primary glioma cells than CAR. 17902184 2007