CYBB, cytochrome b-245 beta chain, 1536

N. diseases: 343; N. variants: 75
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.510 AlteredExpression disease BEFREE The mRNA level of NOX2, the key protein complex responsible for reactive oxygen species production, was higher in ESRD-related polymorphonuclear MDSCs. 28215666 2017
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.510 Biomarker disease CTD_human Niacin ameliorates oxidative stress, inflammation, proteinuria, and hypertension in rats with chronic renal failure. 19420110 2009
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.510 Biomarker disease RGD Renal tissue abundance of gp91(phox) subunit of NAD(P)H oxidase was elevated in the untreated CRF group and was partially reduced in the iron dextran-treated CRF group. 15550752 2005