GRK2, G protein-coupled receptor kinase 2, 156

N. diseases: 159; N. variants: 2
Disease: Hyperglycemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.220 Biomarker disease BEFREE The results indicate that FSH enhances CRTC2-mediated gluconeogenesis dependent on AMPK Ser485 phosphorylation via GRK2 in the liver, suggesting an essential role of FSH in the pathogenesis of fasting hyperglycaemia. 29442133 2018
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.220 Biomarker disease BEFREE Tonic inhibition by G protein-coupled receptor kinase 2 of Akt/endothelial nitric-oxide synthase signaling in human vascular endothelial cells under conditions of hyperglycemia with high insulin levels. 24570070 2014
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.220 Biomarker disease RGD Tempol reduces oxidative stress and restores renal dopamine D1-like receptor- G protein coupling and function in hyperglycemic rats. 16478977 2006