SGMS2, sphingomyelin synthase 2, 166929

N. diseases: 45; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity
0.020 Biomarker disease BEFREE Sms2 deficiency also increased insulin sensitivity and ameliorated high-fat diet-induced obesity. 21844222 2011
CUI: C0028754
Disease: Obesity
Obesity
0.020 Biomarker disease BEFREE In this study, we investigated the physiological function of sphingomyelin synthase 2 (SMS2) using SMS2 knock-out mice, and we found that SMS2 deficiency prevents high fat diet-induced obesity and insulin resistance. 21669879 2011