SGMS2, sphingomyelin synthase 2, 166929

N. diseases: 45; N. variants: 1
Disease: Endothelial dysfunction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.030 Biomarker phenotype BEFREE Our previous study demonstrated that sphingomyelin synthase 2 (SMS2) promotes ED. 31212751 2019
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.030 Biomarker phenotype BEFREE Sphingomyelin synthase 2 promotes H2O2-induced endothelial dysfunction by activating the Wnt/β-catenin signaling pathway. 30272329 2018
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.030 AlteredExpression phenotype BEFREE Therefore, SMS2 over-expression might correlate with endothelial dysfunction and aggravate atherosclerotic plaque instability in ApoE KO mice. 22538014 2012