ZNF366, zinc finger protein 366, 167465

N. diseases: 24; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.550 Biomarker disease BEFREE As loss of DC-SCRIPT expression appears an early event in breast cancer development, we here investigated the role of DC-SCRIPT in mammary gland development using wild-type and DC-SCRIPT knockout mice. 31265831 2019
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.550 Biomarker disease BEFREE As loss of DC-SCRIPT expression appears an early event in breast cancer development, we here investigated the role of DC-SCRIPT in mammary gland development using wild-type and DC-SCRIPT knockout mice. 31265831 2019
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.550 Biomarker disease BEFREE ZNF366, involved in estrogen metabolism and progression of breast cancer, is a new biologically plausible candidate for endometriosis. 25722978 2015
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.550 Biomarker disease BEFREE The effect of DC-SCRIPT on breast cancer cell growth and cell cycle arrest was investigated using novel DC-SCRIPT-inducible MCF7 breast cancer cell lines. 25663546 2015
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.550 Biomarker disease BEFREE The effect of DC-SCRIPT on breast cancer cell growth and cell cycle arrest was investigated using novel DC-SCRIPT-inducible MCF7 breast cancer cell lines. 25663546 2015
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.550 Biomarker disease BEFREE ZNF366, involved in estrogen metabolism and progression of breast cancer, is a new biologically plausible candidate for endometriosis. 25722978 2015
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.550 Biomarker disease BEFREE We recently found that DC-SCRIPT is a prognostic marker in breast cancer and a unique NR coregulator differentially regulating different classes of NRs. 22473304 2012
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.550 Biomarker disease BEFREE We recently found that DC-SCRIPT is a prognostic marker in breast cancer and a unique NR coregulator differentially regulating different classes of NRs. 22473304 2012
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.550 AlteredExpression disease BEFREE This study provides a higher level of evidence that DC-SCRIPT is indeed an independent, pure prognostic, factor for primary breast cancer and shows that DC-SCRIPT mRNA expression is most informative for either ESR1-positive and/or ESR2-low pT1 tumors. 21122099 2010
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.550 Biomarker disease CTD_human DC-SCRIPT: nuclear receptor modulation and prognostic significance in primary breast cancer. 20008677 2010
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.550 Biomarker disease CTD_mouse This study provides a higher level of evidence that DC-SCRIPT is indeed an independent, pure prognostic, factor for primary breast cancer and shows that DC-SCRIPT mRNA expression is most informative for either ESR1-positive and/or ESR2-low pT1 tumors. 21122099 2010
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.550 Biomarker disease CTD_human DC-SCRIPT: nuclear receptor modulation and prognostic significance in primary breast cancer. 20008677 2010
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.550 Biomarker disease CTD_mouse This study provides a higher level of evidence that DC-SCRIPT is indeed an independent, pure prognostic, factor for primary breast cancer and shows that DC-SCRIPT mRNA expression is most informative for either ESR1-positive and/or ESR2-low pT1 tumors. 21122099 2010
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.550 AlteredExpression disease BEFREE This study provides a higher level of evidence that DC-SCRIPT is indeed an independent, pure prognostic, factor for primary breast cancer and shows that DC-SCRIPT mRNA expression is most informative for either ESR1-positive and/or ESR2-low pT1 tumors. 21122099 2010
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.510 AlteredExpression group BEFREE DC-SCRIPT mRNA levels from 190 primary ESR1-positive breast tumors were related to global gene expression, followed by gene ontology and pathway analysis. 25663546 2015
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.510 Biomarker group CTD_human DC-SCRIPT: nuclear receptor modulation and prognostic significance in primary breast cancer. 20008677 2010
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.510 Biomarker group CTD_mouse Clinical significance of the nuclear receptor co-regulator DC-SCRIPT in breast cancer: an independent retrospective validation study. 21122099 2010
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.500 Biomarker disease CTD_mouse Clinical significance of the nuclear receptor co-regulator DC-SCRIPT in breast cancer: an independent retrospective validation study. 21122099 2010
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.500 Biomarker disease CTD_human DC-SCRIPT: nuclear receptor modulation and prognostic significance in primary breast cancer. 20008677 2010
CUI: C4704874
Disease: Mammary Carcinoma, Human
Mammary Carcinoma, Human
0.500 Biomarker disease CTD_mouse Clinical significance of the nuclear receptor co-regulator DC-SCRIPT in breast cancer: an independent retrospective validation study. 21122099 2010
CUI: C4704874
Disease: Mammary Carcinoma, Human
Mammary Carcinoma, Human
0.500 Biomarker disease CTD_human DC-SCRIPT: nuclear receptor modulation and prognostic significance in primary breast cancer. 20008677 2010
CUI: C0013146
Disease: Drug abuse
Drug abuse
0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
CUI: C0013170
Disease: Drug habituation
Drug habituation
0.300 Biomarker phenotype CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
CUI: C0013222
Disease: Drug Use Disorders
Drug Use Disorders
0.300 Biomarker group CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010
Organic Mental Disorders, Substance-Induced
0.300 Biomarker disease CTD_human Genome wide association for addiction: replicated results and comparisons of two analytic approaches. 20098672 2010