DRD2, dopamine receptor D2, 1813

N. diseases: 437; N. variants: 42
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 GeneticVariation group GWASCAT Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. 29942085 2018
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 GeneticVariation group BEFREE Our results indicated that polymorphism in DRD2 rs1800497 may play a role in development of MD. 24655768 2014
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 Biomarker group PSYGENET Our data suggest that altered splicing of DRD2 and expression of DRD1 may constitute a pathophysiological mechanism in risk for SCZ and affective disorders. 24322206 2014
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 AlteredExpression group BEFREE Our data suggest that altered splicing of DRD2 and expression of DRD1 may constitute a pathophysiological mechanism in risk for SCZ and affective disorders. 24322206 2014
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 Biomarker group PSYGENET Our results indicated that polymorphism in DRD2 rs1800497 may play a role in development of MD. 24655768 2014
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 GeneticVariation group BEFREE We found no association between DRD2 gene -141Cins/del polymorphism and mood disorders in overall and Caucasian populations (P>0.05). 21130502 2012
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 Biomarker group PSYGENET We found no association between DRD2 gene -141Cins/del polymorphism and mood disorders in overall and Caucasian populations (P>0.05). 21130502 2012
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 Biomarker group PSYGENET Some evidence implicates methylation of the promoter regions of the DRD2 and HTR2A genes in schizophrenia and mood disorders as well. 15108180 2004
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 GeneticVariation group BEFREE Some evidence implicates methylation of the promoter regions of the DRD2 and HTR2A genes in schizophrenia and mood disorders as well. 15108180 2004
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 GeneticVariation group BEFREE Our results suggest that MAO-A, COMT, 5-HT2A, DRD2, and DRD4 gene variants are not involved in susceptibility toward different time courses in mood disorders. 11992560 2002
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 GeneticVariation group BEFREE Positive association of dopamine D2 receptor polymorphism with bipolar affective disorder in a European Multicenter Association Study of affective disorders. 11857579 2002
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 Biomarker group PSYGENET Our results suggest that MAO-A, COMT, 5-HT2A, DRD2, and DRD4 gene variants are not involved in susceptibility toward different time courses in mood disorders. 11992560 2002
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 GeneticVariation group BEFREE Although less intensively studied than substance use disorders, the DRD2 gene has been implicated in Tourette's syndrome (TS), post-traumatic stress disorder (PTSD) and certain symptoms associated with affective disorders and schizophrenia. 11256581 2000
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 GeneticVariation group BEFREE In our sample DRD2 variants did not markedly influence psychopathology among mood disorder subjects. 10402492 1999
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 GeneticVariation group BEFREE DRD2, DRD4 and GABRA1 variants therefore do not appear to be associated with the outcome of lithium prophylaxis in mood disorders. 10512150 1999
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 Biomarker group BEFREE Our finding provides evidence for the involvement of DRD2 in a disorder of the central nervous system and should lead to further insight into the function of the dopaminergic system in dystonia and other movement and mood disorders. 10220438 1999
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 Biomarker group BEFREE These results do not support a major role for the DRD2 gene in the etiology of either bipolar or unipolar affective disorders. 9754623 1998
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 GeneticVariation group BEFREE Further association study on dopamine D2 receptor variant S311C in schizophrenia and affective disorders. 8723039 1996
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.500 GeneticVariation group BEFREE We investigated a variant of the dopamine D2 receptor gene (Ser311/Cys311 substitution) in Caucasian patients with schizophrenia (n = 273), delusional disorder (n = 62), bipolar I affective disorder (n = 63), and controls (n = 255). 8837713 1996