AGT, angiotensinogen, 183

N. diseases: 765; N. variants: 43
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003811
Disease: Cardiac Arrhythmia
Cardiac Arrhythmia
0.330 Biomarker phenotype BEFREE Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension. 29570510 2018
CUI: C0003811
Disease: Cardiac Arrhythmia
Cardiac Arrhythmia
0.330 Biomarker phenotype BEFREE The use of nitrates, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, aldosterone antagonists, beta-blockers, digoxin, and positive inotropic drugs; treatment of arrhythmias and mechanical complications; and indications for use of implantable cardioverter-defibrillators and cardiac resynchronization is discussed. 28602369 2017
CUI: C0003811
Disease: Cardiac Arrhythmia
Cardiac Arrhythmia
0.330 Biomarker phenotype BEFREE Efficacy of angiotensin II type 1 receptor blockade on reperfusion-induced arrhythmias and mortality early after myocardial infarction is increased in transgenic rats with cardiac angiotensin II type 1 overexpression. 11904535 2002
CUI: C0003811
Disease: Cardiac Arrhythmia
Cardiac Arrhythmia
0.330 Therapeutic phenotype CTD_human To test the hypothesis that angiotensin II (Ang II) in the central nervous system modulates catecholamine-induced cardiac arrhythmias and to determine whether endogenous opioids are operative in this action, arrhythmias were produced in male Wistar rats, by continuous infusion of epinephrine at incremental doses until the development of fatal arrhythmias that were usually ventricular fibrillation. 1654493 1991
CUI: C0003811
Disease: Cardiac Arrhythmia
Cardiac Arrhythmia
0.330 Biomarker phenotype CTD_human To test the hypothesis that angiotensin II (Ang II) in the central nervous system modulates catecholamine-induced cardiac arrhythmias and to determine whether endogenous opioids are operative in this action, arrhythmias were produced in male Wistar rats, by continuous infusion of epinephrine at incremental doses until the development of fatal arrhythmias that were usually ventricular fibrillation. 1654493 1991
CUI: C0003811
Disease: Cardiac Arrhythmia
Cardiac Arrhythmia
0.330 Therapeutic phenotype CTD_human Cardiac arrhythmias are ameliorated by local inhibition of angiotensin formation and bradykinin degradation with the converting-enzyme inhibitor ramipril. 2535056 1989
CUI: C0003811
Disease: Cardiac Arrhythmia
Cardiac Arrhythmia
0.330 Biomarker phenotype CTD_human Cardiac arrhythmias are ameliorated by local inhibition of angiotensin formation and bradykinin degradation with the converting-enzyme inhibitor ramipril. 2535056 1989