|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The hypertensives with angiotensin II >49 pg/mL were at the highest risk of CHD.
|
30917708 |
2019 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The relationship among angiotensinogen genes polymorphisms and hs-CRP and coronary artery disease.
|
30912862 |
2019 |
|
Coronary heart disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
These 11 therapies were for patients with heart failure (angiotensin-converting-enzyme inhibitors, angiotensin II receptor blockers, aldosterone receptor antagonists and digoxin), stable coronary artery disease (intensive statin therapy), asthma exacerbations (early inhaled corticosteroids in the emergency department and anticholinergics), chronic obstructive pulmonary disease (long-acting muscarinic antagonists and long-acting beta-2 adrenoceptor agonists) and schizophrenia (second-generation antipsychotics and depot/maintenance antipsychotics).
|
30045724 |
2018 |
|
Coronary heart disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Comparative Effectiveness of Combination Therapy with Statins and Angiotensin-Converting Enzyme Inhibitors versus Angiotensin II Receptor Blockers in Patients with Coronary Heart Disease: A Nationwide Population-Based Cohort Study in Korea.
|
30225928 |
2018 |
|
Coronary heart disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Angiotensin II receptor blockers versus angiotensin-converting enzyme inhibitors in patients with stable coronary artery disease: Prevalence, correlates, and prognostic impact (from the CORONOR study).
|
27283338 |
2017 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Relationship of the rs1799752 polymorphism of the angiotensin-converting enzyme gene and the rs699 polymorphism of the angiotensinogen gene to the process of in-stent restenosis in a population of Polish patients with stable coronary artery disease.
|
27162064 |
2016 |
|
Coronary heart disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
We assessed possible effect modification by genetic polymorphisms in ALAD, HFE, HMOX1, VDR, GSTP1, GSTT1, GSTM1, APOE, AGTR1 and AGT individually and as the genetic risk score (GRS) on the association between cumulative lead exposure and incident coronary heart disease (CHD) events.
|
27584680 |
2016 |
|
Coronary heart disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Additionally, the protein level of angiotensinogen (AGT) in the ascending aorta and the plasma concentration of Ang II were detected by Western blot and radioimmunoassay, respectively, in ATAA and coronary heart disease patients.
|
25955575 |
2015 |
|
Coronary heart disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Association of angiotensin II type I and type II receptor genes polymorphisms with the presence of premature coronary disease and metabolic syndrome.
|
24385301 |
2014 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Additionally, lncRNAs have been associated with angiotensin II actions and with vascular diseases, including coronary heart disease and atherosclerosis. miRNAs, well studied in various vascular diseases, have also been recently shown to be differentially expressed in the biofluids of patients with vascular disease and mediate cell-cell communication.
|
24614861 |
2014 |
|
Coronary heart disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Disease association analysis revealed that haplotype AGT influences CHD risk (OR 2.4, 95 % CI 1.23-4.84, P = 0.006) which exacerbates after correcting the confounding effects of risk variables (OR 2.5, 95 % CI 1.27-4.99, P = 0.004).
|
24965144 |
2014 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In this study, the authors performed a meta-analysis to clarify the associations between AGT polymorphisms and CHD risk among the Chinese population.
|
22791700 |
2013 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The M235T single nucleotide polymorphism in the angiotensinogen gene is associated with coronary artery calcium in patients with a family history of coronary artery disease.
|
23137822 |
2013 |
|
Coronary heart disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Angiotensinogen, one of the most important proteins in the renin-angiotensin system, plays a key role in the progress of coronary heart disease and myocardial infarction (MI).
|
23666149 |
2013 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Angiotensinogen gene M235T polymorphism and risk of coronary artery disease: a meta-analysis.
|
22842872 |
2012 |
|
Coronary heart disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Considerable progress in our understanding of the role of the angiotensin II type 2 (AT(2)) receptor in the development of cardiac hypertrophy and coronary artery disease has been achieved using in vitro and in vivo animal models.
|
19861351 |
2010 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Interaction of gender, hypertension, and the angiotensinogen gene haplotypes on the risk of coronary artery disease in a large angiographic cohort.
|
18653189 |
2009 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
There were significant interactions between sex and AGT1R 1166 C-allele (p = 0.008) and AGT M235T (p = 0.03) in models for CHD.
|
19327134 |
2009 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The M235T polymorphism in the AGT gene and CHD risk: evidence of a Hardy-Weinberg equilibrium violation and publication bias in a meta-analysis.
|
18575631 |
2008 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
LHGDN |
The M235T polymorphism in the AGT gene and CHD risk: evidence of a Hardy-Weinberg equilibrium violation and publication bias in a meta-analysis.
|
18575631 |
2008 |
|
Coronary heart disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Therefore, we analyzed the angiotensinogen gene as a modifier gene for coronary heart disease risk in patients with familial hypercholesterolemia.
|
18300856 |
2008 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The M235T polymorphism of the AGT gene modifies the risk of coronary artery disease associated with the presence of hypercholesterolemia.
|
18409009 |
2008 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
LHGDN |
Therefore, we analyzed the angiotensinogen gene as a modifier gene for coronary heart disease risk in patients with familial hypercholesterolemia.
|
18300856 |
2008 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We performed a meta-analysis of 43 associations studies on 2 angiotensinogen polymorphisms (M235T and T174M) and risk of CHD published before March 2007, including a total of 13,478 CHD cases and 17,024 controls.
|
17846284 |
2007 |
|
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The angiotensinogen M235T variant was analyzed in 871 consecutive patients with clinically suspected coronary artery disease submitted to coronary angiography study.
|
16045904 |
2005 |