AGT, angiotensinogen, 183

N. diseases: 765; N. variants: 43
Disease: Focal glomerulosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017668
Disease: Focal glomerulosclerosis
Focal glomerulosclerosis 		0.540 Biomarker disease RGD Role of intrarenal angiotensin system activation, oxidative stress, inflammation, and impaired nuclear factor-erythroid-2-related factor 2 activity in the progression of focal glomerulosclerosis. 21357516 2011
CUI: C0017668
Disease: Focal glomerulosclerosis
Focal glomerulosclerosis 		0.540 AlteredExpression disease BEFREE In animal models for human FSGS (doxorubicin nephropathy) and increased renin-angiotensin system activity (Ren2 transgenic rats), glomerular TRPC6 expression was increased in an AngII-dependent manner. 21839714 2011
CUI: C0017668
Disease: Focal glomerulosclerosis
Focal glomerulosclerosis 		0.540 Biomarker disease CTD_human Pressure-induced renal injury in angiotensin II versus norepinephrine-induced hypertensive rats. 19858406 2009
CUI: C0017668
Disease: Focal glomerulosclerosis
Focal glomerulosclerosis 		0.540 GeneticVariation disease LHGDN Effects of the genetic polymorphisms of the renin-angiotensin system on focal segmental glomerulosclerosis. 14610337 2003
CUI: C0017668
Disease: Focal glomerulosclerosis
Focal glomerulosclerosis 		0.540 GeneticVariation disease BEFREE We analyzed the influence of angiotensin-converting enzyme (ACE) I/D, angiotensinogen (AGT) M235T and angiotensin-II-type-1 receptor (AT1R) A1166C genetic polymorphisms on the clinical course of focal segmental glomerulosclerosis (FSGS). 14610337 2003
CUI: C0017668
Disease: Focal glomerulosclerosis
Focal glomerulosclerosis 		0.540 AlteredExpression disease BEFREE Intra-graft angiotensinogen gene expression was significantly elevated in R-FSGS (30.5 + 8.8 ag/fg R-FSGS vs. 16.0 + 4.7 NON-FSGS, P=0.009). 11045652 2000
CUI: C0017668
Disease: Focal glomerulosclerosis
Focal glomerulosclerosis 		0.540 GeneticVariation disease BEFREE The AT1R and angiotensinogen gene polymorphisms are not associated with progression of renal disease in FSGS. 9853248 1998