AGT, angiotensinogen, 183

N. diseases: 765; N. variants: 43
Disease: Pulmonary Fibrosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.550 Biomarker disease BEFREE This study investigates the potential link between AngII-induced autophagy in the regulation of NLRP3 inflammasome/IL-1β axis in lung fibrosis. 29486589 2019
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.550 Therapeutic disease CTD_human Targeting the RAS axis alleviates silicotic fibrosis and Ang II-induced myofibroblast differentiation via inhibition of the hedgehog signaling pathway. 31181250 2019
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.550 Therapeutic disease CTD_human Angiotensin-(1-7)-mediated Mas1 receptor/NF-κB-p65 signaling is involved in a cigarette smoke-induced chronic obstructive pulmonary disease mouse model. 28960804 2018
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.550 Biomarker disease BEFREE In vivo, AngII exacerbated bleomycin (BLM)-induced lung fibrosis in rats, and elevated mir-21 and the NLRP3 inflammasome. 29084974 2017
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.550 Therapeutic disease RGD Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis protects against lung fibrosis by inhibiting the MAPK/NF-κB pathway. 24168260 2014
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.550 GeneticVariation disease BEFREE It is also the first to relate the effect of gender in lung fibrosis with polymorphisms in AGT. 23715995 2013
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.550 Biomarker disease BEFREE Angiotensin II plays a critical role in diabetic pulmonary fibrosis most likely via activation of NADPH oxidase-mediated nitrosative damage. 21487074 2011
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis 		0.550 AlteredExpression disease BEFREE The angiotensin II receptor 2 is expressed and mediates angiotensin II signaling in lung fibrosis. 17630322 2007