AGT, angiotensinogen, 183

N. diseases: 765; N. variants: 43
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 Biomarker disease BEFREE Coexistence effect of hypertension and angiotensin II on the risk of coronary heart disease: a population-based prospective cohort study among Inner Mongolians in China. 30917708 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 GeneticVariation disease BEFREE The relationship among angiotensinogen genes polymorphisms and hs-CRP and coronary artery disease. 30912862 2019
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 Biomarker disease BEFREE Comparative Effectiveness of Combination Therapy with Statins and Angiotensin-Converting Enzyme Inhibitors versus Angiotensin II Receptor Blockers in Patients with Coronary Heart Disease: A Nationwide Population-Based Cohort Study in Korea. 30225928 2018
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 GeneticVariation disease GWASCAT Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. 29212778 2018
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 Biomarker disease BEFREE These 11 therapies were for patients with heart failure (angiotensin-converting-enzyme inhibitors, angiotensin II receptor blockers, aldosterone receptor antagonists and digoxin), stable coronary artery disease (intensive statin therapy), asthma exacerbations (early inhaled corticosteroids in the emergency department and anticholinergics), chronic obstructive pulmonary disease (long-acting muscarinic antagonists and long-acting beta-2 adrenoceptor agonists) and schizophrenia (second-generation antipsychotics and depot/maintenance antipsychotics). 30045724 2018
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 Biomarker disease BEFREE Angiotensin II receptor blockers versus angiotensin-converting enzyme inhibitors in patients with stable coronary artery disease: Prevalence, correlates, and prognostic impact (from the CORONOR study). 27283338 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 Biomarker disease BEFREE Randomized, active controlled parallel group trials were included if they compared CCBs with α-blockers, β-blockers, angiotensin II receptor blockers, angiotensin-converting enzyme inhibitors, or diuretics, had a follow-up of ≥6 months, and had assessments of blood pressure (BP) and CV events [all-cause death, CV death, major CV events (myocardial infarction, MI; congestive heart failure, CHF; stroke; and CV death), MI, stroke, or CHF] in patients with baseline systolic/diastolic BP ≥140/≥90 mm Hg with either concomitant previous stroke and/or CAD. 26588586 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 GeneticVariation disease BEFREE Simultaneous Genotyping of the rs4762 and rs699 Polymorphisms in Angiotensinogen Gene and Correlation with Iranian CAD Patients with Novel Hexa-primer ARMS-PCR. 28828324 2017
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 GeneticVariation disease BEFREE The purpose of this study was to evaluate the association of common polymorphisms in endothelial nitric oxide synthesis (eNOS; G894T) and renin-angiotensin-aldosterone system (angiotensin converting enzyme [ACE]-I/D, angiotensinogen-T704C, and angiotensin II receptor type 1-A1166C) as risk factors in the pathogenesis of coronary artery disease (CAD) in Bulgarian patients. 26670794 2016
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 GeneticVariation disease BEFREE Relationship of the rs1799752 polymorphism of the angiotensin-converting enzyme gene and the rs699 polymorphism of the angiotensinogen gene to the process of in-stent restenosis in a population of Polish patients with stable coronary artery disease. 27162064 2016
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 GeneticVariation disease BEFREE The aim of the present study was to evaluate the role of AGT and REN gene polymorphisms as susceptibility markers for coronary artery disease (CAD) and/or restenosis after coronary stent placement in a group of Mexican patients. 26102248 2015
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 Biomarker disease BEFREE Additionally, the protein level of angiotensinogen (AGT) in the ascending aorta and the plasma concentration of Ang II were detected by Western blot and radioimmunoassay, respectively, in ATAA and coronary heart disease patients. 25955575 2015
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 Biomarker disease BEFREE Association of angiotensin II type I and type II receptor genes polymorphisms with the presence of premature coronary disease and metabolic syndrome. 24385301 2014
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 GeneticVariation disease BEFREE Additionally, lncRNAs have been associated with angiotensin II actions and with vascular diseases, including coronary heart disease and atherosclerosis. miRNAs, well studied in various vascular diseases, have also been recently shown to be differentially expressed in the biofluids of patients with vascular disease and mediate cell-cell communication. 24614861 2014
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 GeneticVariation disease BEFREE The M235T single nucleotide polymorphism in the angiotensinogen gene is associated with coronary artery calcium in patients with a family history of coronary artery disease. 23137822 2013
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 GeneticVariation disease BEFREE AGT gene polymorphisms (M235T, T174M) are associated with coronary heart disease in a Chinese population. 22791700 2013
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 Biomarker disease BEFREE Angiotensinogen, one of the most important proteins in the renin-angiotensin system, plays a key role in the progress of coronary heart disease and myocardial infarction (MI). 23666149 2013
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 GeneticVariation disease BEFREE In this study, we employed TaqMan genotyping assays to evaluate the role of 8 AGT variants in primary hypertension (HTN), type 2 diabetes mellitus (T2DM), and obesity as a possible trigger of coronary artery disease (CAD) in a population of 4615 angiographed native Saudi individuals. 23497386 2013
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 GeneticVariation disease BEFREE Angiotensinogen gene M235T polymorphism and risk of coronary artery disease: a meta-analysis. 22842872 2012
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 GeneticVariation disease BEFREE The AGT M235T polymorphism associates with AMI risk and influences CAD severity. 20663844 2011
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 GeneticVariation disease BEFREE To determine the prognostic significance of a combination of three common polymorphisms of RAS genes (angiotensin converting enzyme - ACE Ins/Del, angiotensin receptor type 1 - AGT1R A1166C and angiotensinogen - ATG M235T) in patients with CAD. 21769789 2011
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 GeneticVariation disease BEFREE The frequency of angiotensinogen (AGT) TT and T allele in patients with CAD was significantly higher (P < .05) than in controls (22% vs 6%and 47% vs23%, respectively). 20547537 2011
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 GeneticVariation disease BEFREE Four polymorphisms, located in the ACE (rs4291), angiotensinogen (rs5049) and (pro)renin receptor (rs2968915; rs5981008) genes were significantly associated with hypertension in two vascular disease populations of CAD (EUROPA) and cerebrovascular disease (PROGRESS; n = 3571). 21157371 2011
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 Biomarker disease BEFREE We examined the association of polymorphisms of angiotensin-converting enzyme (ACE), angiotensinogen (AGT), and angiotensin II type 1 receptor (AT(1) receptor) with severe CAD in CABG patients. 20223792 2010
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.200 GeneticVariation disease BEFREE Since there are no existing data for the Tunisian population, we investigated the association between these polymorphisms (angiotensin-converting enzyme [ACE] insertion/deletion [Ins/Del]; the angiotensinogen T174M and M235T; and the angiotensin II type 1 receptor A1166C polymorphisms) and CAD in Tunisians. 20854100 2010