EDN1, endothelin 1, 1906

N. diseases: 679; N. variants: 23
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.520 Biomarker disease BEFREE Previous studies demonstrated that cultured smooth muscle cells from corpus cavernosum display significantly altered K+ channel function, PGE-induced cAMP accumulation, and endothelin-1 induced Ca2+ mobilization that are consistent with the pathophysiology of erectile dysfunction. 8858394 1996
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.520 Biomarker disease BEFREE To evaluate the protective role of bosentan (BOS), an endothelin-1 (ET-1) receptor antagonist, and to show the changes in rats with experimentally induced diabetic erectile dysfunction (ED), a total of 24 albino Wistar rats were allocated into four groups. 27145076 2017
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.520 Biomarker disease RGD Peripheral mechanisms of erectile dysfunction in a rat model of chronic cocaine use. 17420087 2007
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.520 Biomarker disease CTD_human Altered growth factor expression in the aging penis: the Brown-Norway rat model. 12002441 2002